Evidence map›Paper›PMID 31905773›Full record

ArticleCancers2019

Retropharyngeal Lymph Node Involvement in Oropharyngeal Carcinoma: Impact upon Risk of Distant Metastases and Survival Outcomes.

Zsuzsanna Iyizoba-Ebozue, Louise J Murray, Moses Arunsingh, Karen E Dyker, Sriram Vaidyanathan, Andrew F Scarsbrook, Robin J D Prestwich

Abstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Long-term functional and nutritional outcomes in patients with retropharyngeal lymph node-positive hypopharyngeal cancer treated with concurrent chemoradiotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Is the retropharyngeal lymph node the first echelon node for carcinoma tonsil? Prospective evaluation and literature review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zsuzsanna Iyizoba-EbozueDepartment of Clinical Oncology, Leeds Cancer Centre, Leeds LS97TF, UK.
Louise J MurrayDepartment of Clinical Oncology, Leeds Cancer Centre, Leeds LS97TF, UK.
Moses ArunsinghDepartment of Clinical Oncology, Leeds Cancer Centre, Leeds LS97TF, UK.
Karen E DykerDepartment of Clinical Oncology, Leeds Cancer Centre, Leeds LS97TF, UK.
Sriram VaidyanathanDepartment of Nuclear Medicine and Radiology, Leeds Cancer Centre, Leeds LS97TF, UK.
Andrew F ScarsbrookLeeds Institute of Medical Research at St James's, University of Leeds, Leeds LS97TF, UK.
Robin J D PrestwichDepartment of Clinical Oncology, Leeds Cancer Centre, Leeds LS97TF, UK.ORCID 0000-0002-7872-2826

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The influence of retropharyngeal lymph node (RPLN) involvement on prognosis in oropharyngeal carcinoma remains poorly defined. The aim of this study was to assess the impact of RPLN involvement upon outcomes. A single-centre retrospective analysis of 402 patients with oropharyngeal carcinoma treated nonsurgically between 2010 and 2017 was performed. All had a baseline 2-[fluorine-18]-fluoro-2-deoxy-d-glucose (FDG) PET-CT and contrast-enhanced MRI and/or CT. RPLN status was determined by radiology review of cases with reported abnormal RPLN. Multivariate backwards logistic regression was used to examine impact on outcomes of factors. Abnormal RPLNs were identified in 40/402 (10%) of patients. Median follow up was 42.9 months. RPLN involvement was associated with inferior 3 year outcomes for overall survival (OS) (67.1% vs. 79.1%,

Indexed as

chemotherapydistant metastaseslymph nodeoropharynx cancerradiotherapyretropharyngealsurvival

Identifiers

PMID31905773
PMCPMC7016660

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.