Evidence map›Paper›PMID 31905769›Full record

ReviewJournal of clinical medicine2019

Radiolabeled PET/MRI Nanoparticles for Tumor Imaging.

Ernesto Forte, Dario Fiorenza, Enza Torino, Angela Costagliola di Polidoro, Carlo Cavaliere, Paolo A Netti, Marco Salvatore, Marco Aiello

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed.

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  13. Article
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  15. Green Synthesis of Metal Nanoparticles UsingNanotechnology, science and applications · 2025
    Review
  16. The use of PET/MRI in radiotherapy.Insights into imaging · 2024
    Review
  17. Review
  18. Recent Advances inInternational journal of molecular sciences · 2023
    Review
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ernesto ForteIRCCS SDN, Via Gianturco 113, 80143 Naples, Italy.
Dario FiorenzaIRCCS SDN, Via Gianturco 113, 80143 Naples, Italy.
Enza TorinoDepartment of Chemical Engineering, Materials and Industrial Production, University of Naples Federico II, P.le Tecchio 80, 80125 Naples, Italy.ORCID 0000-0002-8905-1925
Angela Costagliola di PolidoroDepartment of Chemical Engineering, Materials and Industrial Production, University of Naples Federico II, P.le Tecchio 80, 80125 Naples, Italy.
Carlo CavaliereIRCCS SDN, Via Gianturco 113, 80143 Naples, Italy.
Paolo A NettiDepartment of Chemical Engineering, Materials and Industrial Production, University of Naples Federico II, P.le Tecchio 80, 80125 Naples, Italy.
Marco SalvatoreIRCCS SDN, Via Gianturco 113, 80143 Naples, Italy.
Marco AielloIRCCS SDN, Via Gianturco 113, 80143 Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of integrated positron emission tomography (PET)/ magnetic resonance imaging (MRI) scanners opened a new scenario for cancer diagnosis, treatment, and follow-up. Multimodal imaging combines functional and morphological information from different modalities, which, singularly, cannot provide a comprehensive pathophysiological overview. Molecular imaging exploits multimodal imaging in order to obtain information at a biological and cellular level; in this way, it is possible to track biological pathways and discover many typical tumoral features. In this context, nanoparticle-based contrast agents (CAs) can improve probe biocompatibility and biodistribution, prolonging blood half-life to achieve specific target accumulation and non-toxicity. In addition, CAs can be simultaneously delivered with drugs or, in general, therapeutic agents gathering a dual diagnostic and therapeutic effect in order to perform cancer diagnosis and treatment simultaneous. The way for personalized medicine is not so far. Herein, we report principles, characteristics, applications, and concerns of nanoparticle (NP)-based PET/MRI CAs.

Indexed as

3D reconstructionhybrid imagingin vivo imagingmultimodal imagingnanoparticlespositron emission tomography/magnetic resonance imaging (PET/MRI), nanotechnology

Identifiers

PMID31905769
PMCPMC7019574

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.