Trial reportNutrients2019
Is There a Link between Zinc Intake and Status with Plasma Fatty Acid Profile and Desaturase Activities in Dyslipidemic Subjects?
Trial report in Nutrients, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 38 citations in OpenAlex.
- Change in Association Between Minerals, Fatty Acids and Oxidative Stress Parameters in Wistar Rats with Different Diets.Animals : an open access journal from MDPI · 2026Article
- Development of an open-access food atlas with nutrient composition and recipes in Argentina: The Smart24Food Atlas.PloS one · 2026Article
- Effect of calcium salt of flaxseed oil and zinc-methionine supplementation on growth performance, digestibility, feeding behavior, and rumen and blood parameters of fattening lambs.Tropical animal health and production · 2025Article
- Zinc as a Modulator of Male Fertility: Interplay Between Lipid Metabolism, Oxidative Stress, and Sperm Function.Biological trace element research · 2025Review
- Fatty Acid Profile and Desaturase Activity in Obesity: Roles, Mechanisms, and Clinical Relevance.Metabolites · 2025Review
- Factorial analysis of zinc serum levels, fatty acids, oxidative stress parameters and supplementation on assisted reproductive technology outcome.Journal of medical biochemistry · 2025Article
- White Tea Consumption Alleviates Anthropometric and Metabolic Parameters in Obese Patients.Medicina (Kaunas, Lithuania) · 2024Article
- Current Insights into the Effects of Dietary α-Linolenic Acid Focusing on Alterations of Polyunsaturated Fatty Acid Profiles in Metabolic Syndrome.International journal of molecular sciences · 2024Review
- Fatty Acid Profile and Dietary Value of Thigh Meat of Broiler Chickens Receiving Mineral or Organic Forms of Zn.Animals : an open access journal from MDPI · 2024Article
- Article
- Association between Dietary Zinc Intake, Serum Zinc Level and Multiple Comorbidities in Older Adults.Nutrients · 2023Article
- A cross-sectional analysis of zinc and copper levels and their relationship to cardiovascular disease risk markers in Qatar biobank participants.Frontiers in cardiovascular medicine · 2023Article
- Single and Combined Associations of Plasma and Urine Essential Trace Elements (Zn, Cu, Se, and Mn) with Cardiovascular Risk Factors in a Mediterranean Population.Antioxidants (Basel, Switzerland) · 2022Article
- Effects of Dietary α-Linolenic Acid Treatment and the Efficiency of Its Conversion to Eicosapentaenoic and Docosahexaenoic Acids in Obesity and Related Diseases.Molecules (Basel, Switzerland) · 2022Review
- No Association of Hair Zinc Concentration with Coronary Artery Disease Severity and No Relation with Acute Coronary Syndromes.Biomolecules · 2022Article
- Complementary Feeding and Malnutrition among Infants and Young Children Aged 6-23 Months in Rural Areas of China.Nutrients · 2022Article
- The Associations of Erythrocyte Fatty Acids with Whole Blood Mineral Elements in Children.Nutrients · 2022Article
- Existing knowledge on Zn status biomarkers (1963-2021) with a particular focus on FADS1 and FADS2 diagnostic performance and recommendations for further research.Frontiers in nutrition · 2022Review
- Novel Zinc-Related Differentially Methylated Regions in Leukocytes of Women With and Without Obesity.Frontiers in nutrition · 2022Article
- The Influence of Supplementation with Zinc in Micro and Nano Forms on the Metabolism of Fatty Acids in Livers of Rats with Breast Cancer.Nutrients · 2021Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
The prevalence of obesity and dyslipidemia has increased worldwide. The role of trace elements in the pathogenesis of these conditions is not well understood. This study examines the relationship between dietary zinc (Zn) intake and plasma concentrations of Zn, copper (Cu) and iron (Fe) with lipid profile indicators, fatty acid composition in plasma phospholipids and desaturase enzyme activities in a dyslipidemic population. The role of the newly proposed biomarker of Zn status, the linoleic:dihomo-gama-linolenic acid (LA:DGLA) ratio, in predicting Zn status of dyslipidemic subjects has been explored. The study included 27 dyslipidemic adults, 39-72 years old. Trace elements were determined using atomic absorption spectrometry and fatty acid composition by a liquid gas chromatography. Desaturase activities were calculated from product-precursor fatty acid ratios. Dietary data were obtained using 24 h recall questionnaires. Insufficient dietary intake of Zn, low plasma Zn concentrations and an altered Cu:Zn ratio is related to modified fatty acid profile in subjects with dyslipidemia. Plasma Zn status was associated with obesity. There was no correlation between dietary Zn intake and plasma Zn status. The LA:DGLA ratio was inversely linked to dietary Zn intake. Cu, in addition to Zn, may directly or indirectly, affect the activity of desaturase enzymes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.