ArticleMarine drugs2019
Quantitative and Qualitative HPLC Analysis of Mycosporine-Like Amino Acids Extracted in Distilled Water for Cosmetical Uses in Four Rhodophyta.
Article in Marine drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 47 citations in OpenAlex.
- Biosynthesis of UV-Absorbing Mycosporine-like Amino Acids and Transcriptomic Profiling of Differential Gene Expression in Green Microalga Under Abiotic Stresses.International journal of molecular sciences · 2026Article
- Chitosan Nanoformulations of Mycosporine-like Amino Acid (MAA)-Rich Extracts fromInternational journal of molecular sciences · 2025Article
- Diversity of Bioactive Compounds in Microalgae: Key Classes and Functional Applications.Marine drugs · 2025Review
- Biological Effects of Polysaccharides fromPharmaceutics · 2025Article
- Optimizing the Extraction of Bioactive Compounds fromMarine drugs · 2024Article
- The Role of Nitrate Supply in Bioactive Compound Synthesis and Antioxidant Activity in the Cultivation ofMarine drugs · 2024Article
- Recent Advances and Future Prospects of Mycosporine-like Amino Acids.Molecules (Basel, Switzerland) · 2023Review
- Article
- Green Synthesis of Silver Nanoparticles and Its Combination withNanomaterials (Basel, Switzerland) · 2023Article
- Enhancing Bioproducts in Seaweeds via Sustainable Aquaculture: Antioxidant and Sun-Protection Compounds.Marine drugs · 2022Article
- Fast and Efficient Separation of Eleven Mycosporine-like Amino Acids by UHPLC-DAD and Their Quantification in Diverse Red Algae.Marine drugs · 2022Article
- Extraction, Isolation and Characterization of Mycosporine-like Amino Acids from Four Species of Red Macroalgae.Marine drugs · 2021Article
- Analysis of the Mycosporine-Like Amino Acid (MAA) Pattern of the Salt Marsh Red AlgaMarine drugs · 2021Article
- Mycosporine-Like Amino Acids (MAAs): Biology, Chemistry and Identification Features.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Mycosporine-Like Amino Acids from Marine Resource.Marine drugs · 2021Article
- Cyanobacteria and Red Macroalgae as Potential Sources of Antioxidants and UV Radiation-Absorbing Compounds for Cosmeceutical Applications.Marine drugs · 2020Article
- Efficient Extraction and Antioxidant Capacity of Mycosporine-Like Amino Acids from Red Alga DulseMarine drugs · 2020Article
- Phycocosmetics and Other Marine Cosmetics, Specific Cosmetics Formulated Using Marine Resources.Marine drugs · 2020Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mycosporine-like amino acids (MAAs) have gained considerable attention as highly active photoprotective candidates for human sunscreens. However, more studies are necessary to evaluate the extraction efficiency of these metabolites in solvents compatible with cosmetics and their subsequent analysis by HPLC. In the present study, MAA extraction using distilled water and 20% methanol in four Rhodophyta was investigated. Different re-dissolution solvents and a C8 and C18 columns were tested for the HPLC analysis. Porphyra-334, shinorine, palythine, palythine-serine, asterina-330, and palythinol were identified by HPLC/ESI-MS.These MAAs were better isolated with the C8 column and using methanol as re-dissolution solvents. Regarding total MAAs concentrations, no differences between the two solvents were found. The highest values were observed injecting them directly in the HPLC. According to these results, distilled water could be an excellent extraction solvent in the production of MAAs extracts and quantification of their total concentrations for different uses in the industry. Nevertheless, the extraction of MAAs using 20% methanol and re-dissolution in pure methanol after dryness is the best option to characterize and identify the most common MAAs in these red algae. Our results entail important implications regarding the use of red macroalgae as promising candidates as environment-friendly sources of natural sunscreens.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.