Evidence map›Paper›PMID 31905364›Full record

ArticleAudiology & neuro-otology2019

Amplitude Modulated Noise for Tinnitus Suppression in Tonal and Noise-Like Tinnitus.

Stefan Schoisswohl, Johannes Arnds, Martin Schecklmann, Berthold Langguth, Winfried Schlee, Patrick Neff

Open access · hybridAbstract read
In one paragraph

Article in Audiology & neuro-otology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Article
  3. Tinnitus: Clinical Insights in Its Pathophysiology-A Perspective.Journal of the Association for Research in Otolaryngology : JARO · 2024
    Review
  4. Tinnitus Guidelines and Their Evidence Base.Journal of clinical medicine · 2023
    Article
  5. Article
  6. Reverse Correlation Uncovers More Complete Tinnitus Spectra.IEEE open journal of engineering in medicine and biology · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Stefan SchoisswohlDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.
Johannes ArndsDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.
Martin SchecklmannDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.
Berthold LangguthDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.
Winfried SchleeDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany.
Patrick NeffDepartment of Psychiatry and Psychotherapy, University of Regensburg, Regensburg, Germany, patrick.neff@ukr.de.
University of Regensburg · DEUniversity of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe phenomenon of short-term tinnitus suppression by different forms of acoustic stimulation is referred to as residual inhibition (RI). RI can be triggered in the majority of tinnitus cases and was found to be depending on the used intensity, length or types of sounds. Past research already stressed the impact of noise stimulation as well as the superiority of amplitude modulated (AM) pure tones at the individual tinnitus frequency for RI in tonal tinnitus. Recently a novel approach for the determination of noise-like tinnitus characteristics was proposed.

objectivesThe aim of the present study was to investigate whether in participants with noise-like tinnitus RI can be increased by AM noise stimuli according to the individual tinnitus frequency range.

methodsFor this purpose the individual tinnitus characteristics (noise-like and tonal tinnitus) of 29 people affected by tinnitus (mean age = 55.59, 7 females, mean tinnitus duration = 159.97 months) were assessed via customizable noise-band matching. The objective was to generate bandpass filtered stimuli according to the individual tinnitus sound (individualized bandpass filtered [IBP] sounds). Subsequently, various stimuli differing in bandpass filtering and AM were tested with respect to their potential to induce RI. Participants were acoustically stimulated with 7 different types of stimuli for 3 min each and had to rate the loudness of their tinnitus after each stimuli.

resultsResults indicate a general efficacy of noise stimuli for the temporary suppression of tinnitus, but no significant differences between AM and unmodulated IBP. Significantly better effects were observed for the subgroup with noise-like tinnitus (n = 14), especially directly after stimulation offset.

conclusionsThe study at hand provides further insights in potential mechanisms behind RI for different types of tinnitus. Beyond that, derived principles may qualify for new or extend current tinnitus sound therapies.

Indexed as

NoiseAcoustic StimulationAdultAgedAudiometryAudiometry, Pure-ToneFemaleHumansMaleMiddle AgedSoundTinnitusTreatment OutcomeYoung AdultAmplitude modulationBandpass filterNoiseResidual inhibitionTinnitus

Identifiers

PMID31905364
PMCPMC6959056
OpenAlexW2998981883

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.