Evidence map›Paper›PMID 31905308›Full record

ArticleJournal of dental research2020

Heritability of Caries Scores, Trajectories, and Disease Subtypes.

S Haworth, A Esberg, P Lif Holgerson, R Kuja-Halkola, N J Timpson, P K E Magnusson, P W Franks, I Johansson

Open access · hybridAbstract readTwin Study
In one paragraph

Article in Journal of dental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  10. Subtypes of early childhood caries predict future caries experience.Community dentistry and oral epidemiology · 2023
    Article
  11. Article
  12. Article
  13. Article
  14. Bacterial community modifies host genetics effect on early childhood caries.medRxiv : the preprint server for health sciences · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Expert consensus on early childhood caries management.International journal of oral science · 2022
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

S HaworthBristol Dental School, University of Bristol, Bristol, UK.ORCID 0000-0001-7793-7326
A EsbergSection of Cariology, Department of Odontology, Umeå University, Umeå, Sweden.ORCID 0000-0002-4430-8125
P Lif HolgersonSection of Pedodontics, Department of Odontology, Umeå University, Umeå, Sweden.
R Kuja-HalkolaDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
N J TimpsonMedical Research Council Integrative Epidemiology Unit, Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
P K E MagnussonDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
P W FranksDepartment of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmö, Sweden.
I JohanssonSection of Cariology, Department of Odontology, Umeå University, Umeå, Sweden.
Umeå University · SEKarolinska Institutet · SEHarvard University · USUniversity of Bristol · GBUniversity Of Bristol Dental Hospital · GB

Funding

Department of Health
6 · The paper itself

Abstract

Previous studies report that dental caries is partially heritable, but there is uncertainty in the magnitude of genetic effects and little understanding of how genetic factors might influence caries progression or caries subtypes. This study aimed to estimate the relative importance of genetic and environmental factors in the etiology of different caries outcomes using a twin-based design. Analysis included up to 41,678 twins in the Swedish Twin Register aged 7 to 97 y, and dental data were obtained from preexisting dental records. The outcome measures were 1) summary indices of caries experience, 2) parameters representing trajectory in caries progression derived from longitudinal modeling, and 3) caries scores in groups of biologically similar tooth surfaces derived from hierarchical clustering of tooth surfaces (termed

Indexed as

Dental CariesToothAdolescentAdultAgedAged, 80 and overChildCluster AnalysisCross-Sectional StudiesHumansMiddle AgedMolarYoung Adultcluster analysisdental caries susceptibilityepidemiologygeneticslongitudinaltwins

Identifiers

PMID31905308
PMCPMC7036480
OpenAlexW2994746417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.