Evidence map›Paper›PMID 31905032›Full record

ArticleAutophagy2020

Crimean-Congo hemorrhagic fever virus replication imposes hyper-lipidation of MAP1LC3 in epithelial cells.

Marie Moroso, Pauline Verlhac, Olivier Ferraris, Aurore Rozières, Caroline Carbonnelle, Stéphane Mély, Hubert P Endtz, Christophe N Peyrefitte, Glaucia Paranhos-Baccalà, Christophe Viret and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
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  4. Review
  5. The role of autophagy in viral infections.Journal of biomedical science · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Marie MorosoCIRI, Centre International de Recherche en Infectiologie, Univ Lyon , Lyon, France.ORCID 0000-0002-7132-6329
Pauline VerlhacCIRI, Centre International de Recherche en Infectiologie, Univ Lyon , Lyon, France.ORCID 0000-0002-1059-4645
Olivier FerrarisCIRI, Centre International de Recherche en Infectiologie, Univ Lyon , Lyon, France.
Aurore RozièresCIRI, Centre International de Recherche en Infectiologie, Univ Lyon , Lyon, France.
Caroline CarbonnelleLaboratoire P4 Inserm-Jean Mérieux, US003 Inserm , Lyon, France.
Stéphane MélyLaboratoire P4 Inserm-Jean Mérieux, US003 Inserm , Lyon, France.ORCID 0000-0002-3278-3455
Hubert P EndtzCIRI, Centre International de Recherche en Infectiologie, Univ Lyon , Lyon, France.
Christophe N PeyrefitteCIRI, Centre International de Recherche en Infectiologie, Univ Lyon , Lyon, France.
Glaucia Paranhos-BaccalàCIRI, Centre International de Recherche en Infectiologie, Univ Lyon , Lyon, France.
Christophe ViretCIRI, Centre International de Recherche en Infectiologie, Univ Lyon , Lyon, France.
Mathias FaureCIRI, Centre International de Recherche en Infectiologie, Univ Lyon , Lyon, France.
Université Claude Bernard Lyon 1 · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crimean-Congo hemorrhagic fever virus (CCHFV) is a virus that causes severe liver dysfunctions and hemorrhagic fever, with high mortality rate. Here, we show that CCHFV infection caused a massive lipidation of LC3 in hepatocytes. This lipidation was not dependent on

Indexed as

AutophagyVirus ReplicationAnimalsAutophagy-Related Protein 5Autophagy-Related Protein 7Beclin-1Chlorocebus aethiopsEpithelial CellsHeLa CellsHemorrhagic Fever, CrimeanHemorrhagic Fever Virus, Crimean-CongoHepatocytesHep G2 CellsHumansLipidsMicrotubule-Associated ProteinsATG5 protein, humanATG7 protein, humanAutophagy-Related Protein 5Autophagy-Related Protein 7Beclin-1BECN1 protein, humanLipidsMAP1LC3A protein, humanMicrotubule-Associated ProteinsSequestosome-1 ProteinSQSTM1 protein, humanAutophagyCCHFVepithelial cellsLC3 lipidationviral infection

Identifiers

PMID31905032
PMCPMC8386629
OpenAlexW2997863593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.