ReviewChemical reviews2020
Reactions of Allylmagnesium Reagents with Carbonyl Compounds and Compounds with C═N Double Bonds: Their Diastereoselectivities Generally Cannot Be Analyzed Using the Felkin-Anh and Chelation-Control Models.
Review in Chemical reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Cu-Catalyzed dynamic kinetic asymmetric allylation enabled enantioselective assembly of sterically congested triaryl tertiary alcohols.Nature communications · 2026Article
- Non-chelation control in allylations of α-oxy ketones using group-14 allylatranes.Nature communications · 2026Article
- Modular assembly of chiral amino acid derivatives and peptides from commonly available feedstocks.Nature communications · 2025Article
- Catalytic 1,2-Migratory Insertion in a Bismuth Redox Platform: Reductive Arylation of Aldehydes.Angewandte Chemie (International ed. in English) · 2025Article
- Catalytic enantioselective total synthesis of antitubercular agents (-)-bedaquiline and (-)-sudapyridine enabled by dynamic kinetic resolution-asymmetric transfer hydrogenation.Chemical science · 2025Article
- Unmasking the halide effect in diastereoselective Grignard reactions applied to C4´ modified nucleoside synthesis.Nature communications · 2025Article
- Biomimetic Synthesis of Azorellolide via Cyclopropylcarbinyl Cation Chemistry.Journal of the American Chemical Society · 2025Article
- Acetal Substitution Reactions: Stereoelectronic Effects, Conformational Analysis, Reactivity vs. Selectivity, and Neighboring-Group Participation.Synlett : accounts and rapid communications in synthetic organic chemistry · 2024Article
- Article
- The Reduction of Carbonyl Compounds with Dicyclopentylzinc: A New Example of Asymmetric Amplifying Autocatalysis.International journal of molecular sciences · 2023Article
- Structural Congeners of Izenamides Responsible for Cathepsin D Inhibition: Insights from Synthesis-Derived Elucidation.Marine drugs · 2023Article
- Stereoselective Construction of Tertiary Homoallyl Alcohols and Ethers by Nucleophilic Substitution at Quaternary Carbon Stereocenters.Angewandte Chemie (International ed. in English) · 2023Article
- Up-Scale Synthesis ofACS omega · 2022Article
- Total synthesis of structurally diverse pleuromutilin antibiotics.Nature chemistry · 2022Article
- Conformationally Biased Ketones React Diastereoselectively with Allylmagnesium Halides.The Journal of organic chemistry · 2022Article
- The 100 facets of the Passerini reaction.Chemical science · 2021Review
- Diastereoselective Additions of Allylmagnesium Reagents to α-Substituted Ketones When Stereochemical Models Cannot Be Used.The Journal of organic chemistry · 2021Article
- Nucleophilicity PredictionThe Journal of organic chemistry · 2021Article
- Evidence against Single-Electron Transfer in the Additions of Most Organomagnesium Reagents to Carbonyl Compounds.The Journal of organic chemistry · 2020Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
This review describes the additions of allylmagnesium reagents to carbonyl compounds and to imines, focusing on the differences in reactivity between allylmagnesium halides and other Grignard reagents. In many cases, allylmagnesium reagents either react with low stereoselectivity when other Grignard reagents react with high selectivity, or allylmagnesium reagents react with the opposite stereoselectivity. This review collects hundreds of examples, discusses the origins of stereoselectivities or the lack of stereoselectivity, and evaluates why selectivity may not occur and when it will likely occur.
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Registered trials
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