ArticleHuman brain mapping2020
Anterior cingulate cortex differently modulates frontoparietal functional connectivity between resting-state and working memory tasks.
Article in Human brain mapping, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 31 citations in OpenAlex.
- Working Memory Impairment Induced by Chemotherapy-A Narrative Review.Brain sciences · 2026Review
- The neural basis of prosocial effort-based decision making in older adults at risk for Alzheimer's disease.medRxiv : the preprint server for health sciences · 2026Article
- Differential connectivity between core hubs underlying demanding executive functions in schizophrenia compared to autism and control adults.Frontiers in psychiatry · 2026Article
- Associations between vitamin D and brain volume in children with autism spectrum disorder.Pediatric research · 2025Article
- Covariance-on-covariance regression.Biometrics · 2025Article
- Comparative analysis of Voxel-based morphometry using T1 and T2-weighted magnetic resonance imaging to explore the relationship between brain structure and cognitive abilities.Experimental brain research · 2025Article
- Olfactory Network Disruptions as Mediators of Cognitive Impairment in De Novo Parkinson's Disease.CNS neuroscience & therapeutics · 2025Article
- Dopamine D2/D3 receptor availability and working memory in stimulant use disorder.The American journal of drug and alcohol abuse · 2025Article
- Functional connectivity gradients of the cingulate cortex.Communications biology · 2023Article
- The Devastating Effects of Sleep Deprivation on Memory: Lessons from Rodent Models.Clocks & sleep · 2023Review
- Interaction Between Memory Load and Experimental Design on Brain Connectivity and Network Topology.Neuroscience bulletin · 2023Article
- Article
- Static and dynamic functional connectome reveals reconfiguration profiles of whole-brain network across cognitive states.Network neuroscience (Cambridge, Mass.) · 2023Article
- Cortical connectivity gradients and local timescales during cognitive states are modulated by cognitive loads.Brain structure & function · 2022Article
- Associations between abstract working memory abilities and brain activity underlying long-term recognition of auditory sequences.PNAS nexus · 2022Article
- From Shorter to Longer Timescales: Converging Integrated Information Theory (IIT) with the Temporo-Spatial Theory of Consciousness (TTC).Entropy (Basel, Switzerland) · 2022Article
- Pupillometry tracks cognitive load and salience network activity in a working memory functional magnetic resonance imaging task.Human brain mapping · 2022Article
- A functional MRI pre-processing and quality control protocol based on statistical parametric mapping (SPM) and MATLAB.Frontiers in neuroimaging · 2022Article
- Capacity differences in working memory based on resting state brain networks.Scientific reports · 2021Article
- Early Stopping in Experimentation With Real-Time Functional Magnetic Resonance Imaging Using a Modified Sequential Probability Ratio Test.Frontiers in neuroscience · 2021Article
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
The brain frontoparietal regions and the functional communications between them are critical in supporting working memory and other executive functions. The functional connectivity between frontoparietal regions are modulated by working memory loads, and are shown to be modulated by a third brain region in resting-state. However, it is largely unknown whether the third-region modulations remain the same during working memory tasks or were largely modulated by task demands. In the current study, we collected functional MRI (fMRI) data when the subjects were performing n-back tasks and in resting-state. We first used a block-designed localizer to define the frontoparietal regions that showed higher activations in the 2-back than the 1-back condition. Next, we performed physiophysiological interaction (PPI) analysis using left and right middle frontal gyrus (MFG) and superior parietal lobule (SPL) regions, respectively, in three continuous-designed runs of resting-state, 1-back, and 2-back conditions. No regions showed consistent modulatory interactions with the seed pairs in the three conditions. Instead, the anterior cingulate cortex (ACC) showed different modulatory interactions with the right MFG and SPL among the three conditions. While the increased activity of the ACC was associated with decreased functional coupling between the right MFG and SPL in resting-state, it was associated with increased functional coupling in the 2-back condition. The observed task modulations support the functional significance of the modulations of the ACC on frontoparietal connectivity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.