Evidence map›Paper›PMID 31904878›Full record

ReviewThe Laryngoscope2021

A Modern Case Sheds Light on a Classical Enigma: Beethoven's Deafness.

Davide Brotto, Renato Fellin, Flavia Sorrentino, Flavia Gheller, Patrizia Trevisi, Roberto Bovo

Abstract readHistorical ArticleReview
PubMed Publisher
In one paragraph

Review in The Laryngoscope, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Aetiology of Ludwig van Beethoven's hearing impairment: hypotheses over the past 100 years - A systematic review.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Does lead take the lead as the best explanation for Beethoven deafness?European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  6. For each hypothesis on the aetiology of Beethoven's hearing disorder, there remain pro's and con's.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  7. Beethoven-life and maladies.Wiener medizinische Wochenschrift (1946) · 2021
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Davide BrottoENT Unit, Neurosciences Department, University of Padua, Padova, Italy.ORCID 0000-0002-6291-4399
Renato FellinDepartment of Internal Medicine, University of Ferrara, Ferrara, Italy.
Flavia SorrentinoENT Unit, Neurosciences Department, University of Padua, Padova, Italy.
Flavia GhellerENT Unit, Neurosciences Department, University of Padua, Padova, Italy.ORCID 0000-0002-0244-8488
Patrizia TrevisiENT Unit, Neurosciences Department, University of Padua, Padova, Italy.
Roberto BovoENT Unit, Neurosciences Department, University of Padua, Padova, Italy.
University of Padua · ITUniversity of Ferrara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two hundred and fifty years have passed since the birth of Ludwig van Beethoven, and the enigma about his hearing loss and overall health status seems to be not completely solved. However, the admission to the hospital of a 64-year-old woman in 2018 with symptoms extremely similar to those experienced by the great composer may add further evidence to a theory previously underestimated. The health issues of the modern patient were found to be due to chronic lead intoxication. The lead was released during daily cooking using a ceramic-coated frying pan with worn surface that poisoned her breakfast most probably for years. Abdominal pain, asthenia, and hearing loss affecting the high frequencies with a many impact on speech intelligibility tormented the patient, as they had Beethoven. An extensive review of the music and medical literature was performed, as well as re-examination of manuscripts, correspondence, and autopsy reports of the famous composer; and great similarities have been found. The soundness of the most-cited classical theories about Beethoven's hearing loss will be discussed. After close scrutiny of the theories, our analysis points toward a progressive sensorineural hearing loss due to lead intoxication as the most probable cause of not only Beethoven's hypoacusis but his overall health status as well. Laryngoscope, 131:179-185, 2021.

Indexed as

Famous PersonsHearing Loss, SensorineuralLead PoisoningFemaleGermanyHistory, 18th CenturyHistory, 19th CenturyHumansMaleMiddle AgedBeethovendeafnesshearing lossleadpoisoning

Identifiers

PMID31904878
OpenAlexW2999615502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.