ArticleAnnals of surgery2021
Endovascular Repair of Blunt Thoracic Aortic Trauma is Associated With Increased Left Ventricular Mass, Hypertension, and Off-target Aortic Remodeling.
Article in Annals of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Left ventricular remodeling and modification of aortic stiffness after endovascular aortic repair: a systematic review and meta-analysis.Langenbeck's archives of surgery · 2026Pooled it
- Stent-graft compliance modulates regional mechanical and structural remodeling of the aorta.Acta biomaterialia · 2026Article
- Windkessel Preserving Aortic Stent Graft Attenuates Left Ventricular Remodelling after Thoracic Endovascular Aortic Repair in a Porcine Model.European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery · 2026Article
- Effect of stent-graft length and compliance on aortic hemodynamics in a bench-top physiological flow circuit.Journal of the mechanical behavior of biomedical materials · 2026Article
- Aortic and cardiovascular remodelling after thoracic endovascular aortic repair for blunt traumatic aortic injury in younger patients: A narrative review of physiological and clinical outcomes.Experimental physiology · 2026Review
- Effect of stent-graft compliance on hemodynamics and aortic stiffening in an in vivo porcine study.Acta biomaterialia · 2026Article
- Investigating the role of structural wall stress in aortic growth prognosis in acute uncomplicated type B aortic dissection.Biomechanics and modeling in mechanobiology · 2025Article
- FREQUENCY OF AORTIC MISCANNULATION DURING FLUOROSCOPY-FREE ENDOVASCULAR NAVIGATION.medRxiv : the preprint server for health sciences · 2025Article
- Endovascular treatment under laparotomy with n-butyl-2-cyanoacrylate in a pediatric traumatic aortic injury: a case report.Journal of cardiothoracic surgery · 2025Article
- Cardiac remodeling and antihypertensive medication changes after thoracic endovascular aortic repair vs open surgical repair.Journal of vascular surgery · 2025Article
- A viscoelastic constitutive framework for aging muscular and elastic arteries.Acta biomaterialia · 2024Article
- The use of 4-dimensional flow magnetic resonance imaging and fluid structure interaction analysis to predict failure of medical therapy in acute uncomplicated type B aortic dissection.JTCVS techniques · 2024Article
- Thoracic Endovascular Aortic RepairAcutely Augments Left Ventricular Biomechanics in An Animal Model: A Mechanism for Postoperative Heart Failure and Hypertension.Annals of vascular surgery · 2023Article
- Traumatic blunt thoracic aortic injury: a 10-year single-center retrospective analysis.Journal of cardiothoracic surgery · 2022Article
- Calcification prevalence in different vascular zones and its association with demographics, risk factors, and morphometry.American journal of physiology. Heart and circulatory physiology · 2021Article
- Short Term Prognosis of Renal Artery Stenosis Secondary to Acute Type B Aortic Dissection With TEVAR.Frontiers in cardiovascular medicine · 2021Article
- Mechanical, structural, and physiologic differences in human elastic and muscular arteries of different ages: Comparison of the descending thoracic aorta to the superficial femoral artery.Acta biomaterialia · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundAortic elasticity creates a cushion that protects the heart from pressure injury, and a recoil that helps perfuse the coronary arteries. TEVAR has become first-line therapy for many aortic pathologies including trauma, but stent-grafts stiffen the aorta and likely increase LV afterload.
objectiveTest the hypothesis that trauma TEVAR is associated with LV mass increase and adverse off-target aortic remodeling.
methodsComputed Tomography Angiography (CTA) scans of 20 trauma TEVAR patients (17 M/3 F) at baseline [age 34.9 ± 18.5 (11.4-71.5) years] and 5.1 ± 3.1 (1.1-12.3) years after repair were used to measure changes in LV mass, LV mass index, and diameters and lengths of the ascending thoracic aorta (ATA). Measurements were compared with similarly-aged control patients without aortic repair (21 M/21 F) evaluated at similar follow-ups.
resultsLV mass and LV mass index of TEVAR patients increased from 138.5 ± 39.6 g and 72.35 ± 15.17 g/m2 to 173.5 ± 50.1 g and 85.48 ± 18.34 g/m2 at the rate of 10.03 ± 12.79 g/yr and 6.25 ± 10.28 g/m2/yr, whereas in control patients LV characteristics did not change. ATA diameters of TEVAR patients increased at a rate of 0.60 ± 0.80 mm/yr, which was 2.4-fold faster than in controls. ATA length in both TEVAR and control patients increased at 0.58 mm/yr. Half of TEVAR patients had hypertension at follow-up compared to only 5% at baseline.
conclusionsTEVAR is associated with LV mass increase, development of hypertension, and accelerated expansile remodeling of the ascending aorta. Although younger trauma patients may adapt to these effects, these changes may be even more important in older patients with other aortic pathologies and diminished baseline cardiac function.
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