ArticlePreventive medicine2020
Prescription opioid misuse among adolescents and emerging adults in the United States: A scoping review.
Article in Preventive medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Opioid Misuse and Suicide-Related Outcomes Among Adolescents and Young Adults: A Systematic Review.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025Pooled it
- Systematic review of the use of prescription and non-prescription psychotropic drugs and their relation with mental health in university population.Frontiers in psychology · 2025Pooled it
- Parental drug use disorders and youth psychopathology: Meta-analytic review.Drug and alcohol dependence · 2023Pooled it
- Selective Personality-Targeted Intervention and the Escalation of Substance Use During Adolescence: A Secondary Analysis of A Cluster-Randomized Clinical Trial.JAMA network open · 2025Trial
- Understanding risk and protective factors associated with opioid misuse among at-risk adolescents and young adults in the emergency department.Drug and alcohol dependence · 2025Trial
- Enhancing risk perception may be insufficient to curtail prescription opioid use and misuse among youth after surgery: A randomized controlled trial.Patient education and counseling · 2022Trial
- Piloting a brief intervention plus mobile boosters for drug use among emerging adults receiving emergency department care.Drug and alcohol dependence · 2021Trial
- Opioid misuse and sexually transmitted infections among U.S. college students: a cross-sectional analysis of the ACHA-NCHA III.BMC public health · 2026Article
- Understanding Opioid Use from Retrospective Accounts of Young Adults in Recovery: Motives, Experiences, and Implications for Prevention.Journal of prevention (2022) · 2026Article
- The multidimensional social ecological needs and service utilization patterns of youth using non-medical prescription opioids: an observational study of routinely collected data in a provincial integrated youth services initiative.Substance abuse treatment, prevention, and policy · 2025Observational
- Investing in Interventions to Prevent Opioid Use Disorder in Adolescents and Young Adults: Start-up Costs from NIDA's HEAL Prevention Initiative.Prevention science : the official journal of the Society for Prevention Research · 2025Article
- US Adolescents' and Young Adults' Sources for Prescription Opioid Misuse: Age, Substance Use, and Mental Health Differences.Pain practice : the official journal of World Institute of Pain · 2025Article
- Adolescents' and Parents' Perspectives on Using the MedSMARxT Families Intervention in Emergency Departments for Opioid Medication Safety Education: Mixed Methods Study.JMIR serious games · 2025Article
- Theory-Based Social Media Intervention for Nonmedical Use of Prescription Opioids in Young Adults: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2025Article
- Article
- Tailoring opioid use prevention content for juvenile diversion programs with adolescents and their caregivers.Journal of substance use and addiction treatment · 2024Article
- Unveiling the link between chronic pain and misuse of opioids and cannabis.Journal of neural transmission (Vienna, Austria : 1996) · 2024Review
- Anxiety and depressive symptoms as predictors of substance use initiation among adolescents living on and near a Tribal reservation in the Great Plains region of the U.S.Frontiers in child and adolescent psychiatry · 2024Article
- Multidisciplinary Strategies for Preventing Opioid Misuse and Escalation by Targeting Mental Health Symptoms and Conditions.Prevention science : the official journal of the Society for Prevention Research · 2023Article
- Economic Evaluation Design within the HEAL Prevention Cooperative.Prevention science : the official journal of the Society for Prevention Research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
The U.S. opioid epidemic is a critical public health problem. As substance use and misuse typically begin in adolescence and emerging adulthood, there is a critical need for prevention efforts for this key developmental period to disrupt opioid misuse trajectories, reducing morbidity and mortality [e.g., overdose, development of opioid use disorders (OUD)]. This article describes the current state of research focusing on prescription opioid misuse (POM) among adolescents and emerging adults (A/EAs) in the U.S. Given the rapidly changing nature of the opioid epidemic, we applied PRISMA Scoping Review (PRISMA-ScR) guidelines to identify empirical articles published in the past 5 years (January 2013-September 2018) from nine databases examining POM among A/EAs (ages 10-25) in the U.S. Seventy-six articles met our inclusion criteria focusing on POM in the following areas: cross-sectional surveys (n = 60), longitudinal cohort studies (n = 5), objective, non-self-reported data sources (n = 9), and interventions (n = 2). Final charted data elements were organized by methodology and sample, with results tables describing design, sample, interventions (where applicable), outcomes, and limitations. Most studies focused on the epidemiology of POM and risk/protective factors, including demographic (e.g., sex, race), individual (e.g., substance use, mental health), and social (e.g., peer substance use) factors. Despite annual national surveys conducted, longitudinal studies examining markers of initiation and escalation of prescription opioid misuse (e.g., repeated overdoses, time to misuse) are lacking. Importantly, few evidence-based prevention or early intervention programs were identified. Future research should examine longitudinal trajectories of POM, as well as adaptation and implementation of promising prevention approaches.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.