Evidence map›Paper›PMID 31904390›Full record

ArticleAppetite2020

Neural correlates of inhibitory control in youth with symptoms of food addiction.

Jillian E Hardee, Camille Phaneuf, Lora Cope, Robert Zucker, Ashley Gearhardt, Mary Heitzeg

Registry-linked trialOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Appetite, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06387719 (Precursors of Binge Eating Disorder in a Clinical Sample of Adolescents With Obesity), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06387719 unknown statusnot on this mapstarted 2023, after this paper: background citation

Precursors of Binge Eating Disorder in a Clinical Sample of Adolescents With Obesity: Early MRI Markers of Brain Reward and Inhibition Processing Dysfunction

Typeobservational_patient_registrySponsorFundació Sant Joan de DéuRan2023 to 2026Enrolled102ConditionsBinge-Eating Disorder, Obesity, Eating Disorders, BEDArmsMagnetic resonance imaging
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Prevalence of food addiction in children and adolescents: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jillian E HardeeUniversity of Michigan, Department of Psychiatry and Addiction Center, 4250 Plymouth Rd, Ann Arbor, MI, 48109, USA. Electronic address: jhardee@med.umich.edu.
Camille PhaneufUniversity of Michigan, Department of Psychology, 530 Church St, Ann Arbor, MI, 48109, USA.
Lora CopeUniversity of Michigan, Department of Psychiatry and Addiction Center, 4250 Plymouth Rd, Ann Arbor, MI, 48109, USA.
Robert ZuckerUniversity of Michigan, Department of Psychiatry and Addiction Center, 4250 Plymouth Rd, Ann Arbor, MI, 48109, USA.
Ashley GearhardtUniversity of Michigan, Department of Psychology, 530 Church St, Ann Arbor, MI, 48109, USA.
Mary HeitzegUniversity of Michigan, Department of Psychiatry and Addiction Center, 4250 Plymouth Rd, Ann Arbor, MI, 48109, USA.
University of Michigan–Ann Arbor · US

Funding

Family Study of Risk for Alcoholism Over the Life CourseR37AA007065 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZUCKER, ROBERT ALPERT · 2003 to 2012
$10.6M
RISK AND COPING IN CHILDREN OF ALCOHOLICSR01AA007065 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEITZEG, MARY M · 1987 to 2017
$6.1M
Brain Endophenotypes Modulating Drug Abuse RiskR01DA027261 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ZUCKER, ROBERT ALPERT · 2009 to 2013
$3.3M
Developmental neurobiological and contextual influences on alcohol use disorderR01AA025790 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEITZEG, MARY M, HICKS, BRIAN M · 2018 to 2022
$2.8M
Developmental and peer effects on the neurobiology of cognitive control and reward processesR01AA024433 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEITZEG, MARY M, HICKS, BRIAN M · 2017 to 2021
$2.4M
Food Marketing Vulnerability and Increased Risk for Weight Gain in AdolescentsR01DK102532 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GEARHARDT, ASHLEY NICOLE · 2015 to 2017
$1.3M
Sex differences in the neural mechanisms of brief interventions for binge drinkingK01AA024804 · NIAAA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HARDEE, JILLIAN ELIZABETH · 2016 to 2020
$830k
NIAAA NIH HHS K01 AA024804NIAAA NIH HHS R01 AA007065NIAAA NIH HHS R01 AA024433NIAAA NIH HHS R01 AA025790NIAAA NIH HHS R37 AA007065NIDA NIH HHS R01 DA027261NIDDK NIH HHS R01 DK102532
6 · The paper itself

Abstract

Prior research has found that food addiction is associated with reward-related neural differences, but research has yet to examine whether there are also neural differences in inhibitory control. This may be particularly relevant during adolescence as it is a key developmental period where difficulties in inhibitory control are more prevalent. The Yale Food Addiction Scale is a self-report questionnaire that applies substance use disorder diagnostic criteria to certain foods that has also been adapted for children. Here we investigate the association between addictive-like eating and brain functioning during inhibitory control in youth. Seventy-six right-handed participants 8.2-17.8 years (44 male) were recruited. Participants performed a go/no-go task during functional magnetic resonance imaging and completed the Yale Food Addiction Scale for Children, after which they were categorized into two groups according to their scores (No Symptom Group = 0; YFAS-C Group: score ≥ 1). Inhibitory control was probed with a contrast of correct no-go versus go trials. An independent-samples t-test comparing groups revealed a significant difference in three primary clusters, all exclusively in the left hemisphere (No Symptom Group > YFAS-C Group): middle temporal gyrus/occipital gyrus, precuneus/calcarine sulcus, and inferior frontal gyrus. Specifically, the YFAS-C Group showed deactivation in all three clusters. Adolescents who endorse food addiction appear to show hypo-activation in response to the inhibitory control portion of a go/no-go task, which suggests possible inhibitory control difficulties.

Indexed as

Behavior, AddictiveBrainFood AddictionInhibition, PsychologicalAdolescentBody Mass IndexBrain MappingChildEatingFeeding BehaviorFemaleFoodHumansMagnetic Resonance ImagingMaleSelf-ControlAdolescentfMRIFood addictionInhibitory controlNeuroimaging

Identifiers

PMID31904390
PMCPMC7024015
OpenAlexW2998144567

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.