ArticleBrain and behavior2020
Associations between personality and whole-brain functional connectivity at rest: Evidence across the adult lifespan.
Article in Brain and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Association between neuroticism and physical activity: a systematic review and meta-analysis.Frontiers in human neuroscience · 2025Pooled it
- How blindness shapes personality: a neuro-ecological account.Frontiers in neuroscience · 2026Article
- Deviation From Typical Brain Activity During Naturalistic Stimulation Is Related to Personality Traits.Psychophysiology · 2025Article
- The Role of Willpower in Major Depressive Disorder: An fMRI Study.Brain and behavior · 2025Article
- Contrastive functional connectivity defines neurophysiology-informed symptom dimensions in major depression.Cell reports. Medicine · 2025Article
- Group-to-individual generalizability and individual-level inferences in cognitive neuroscience.Neuroscience and biobehavioral reviews · 2025Review
- Network-based mapping and neurotransmitter architecture of gray matter correlates of neuroticism.Frontiers in systems neuroscience · 2025Article
- Topological signatures of brain dynamics: persistent homology reveals individuality and brain-behavior links.Frontiers in human neuroscience · 2025Article
- Combined effects of neuroticism and negative emotional context on spontaneous EEG dynamics.Social cognitive and affective neuroscience · 2024Article
- Intrinsic functional connectivity mediates the effect of personality traits on depressive symptoms.PloS one · 2024Article
- Temperament & Character account for brain functional connectivity at rest: A diathesis-stress model of functional dysregulation in psychosis.Molecular psychiatry · 2023Review
- The neural correlates of value hierarchies: a prospective typology based on personal value profiles of emerging adults.Frontiers in psychology · 2023Article
- Reward enhances connectivity between the ventral striatum and the default mode network.NeuroImage · 2022Article
- Relationships between Perfectionism, Extra Training and Academic Performance in Chinese Collegiate Athletes: Mediating Role of Achievement Motivation.International journal of environmental research and public health · 2022Article
- Functional network dynamics and decreased conscientiousness in multiple sclerosis.Journal of neurology · 2022Article
- Lesions in different prefrontal sectors are associated with different types of acquired personality disturbances.Cortex; a journal devoted to the study of the nervous system and behavior · 2022Observational
- The Influence of Physical Exercise on Adolescent Personality Traits: The Mediating Role of Peer Relationship and the Moderating Role of Parent-Child Relationship.Frontiers in psychology · 2022Article
- Default mode network functional connectivity negatively associated with trait openness to experience.Social cognitive and affective neuroscience · 2021Article
- Resting-State Functional Connectivity Associated With Extraversion and Agreeableness in Adolescence.Frontiers in behavioral neuroscience · 2021Article
- Associations between personality and whole-brain functional connectivity at rest: Evidence across the adult lifespan.Brain and behavior · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
introductionPersonality is associated with cognitive, emotional, and social functioning, and can play a role in age-related cognitive decline and dementia risk; however, little is known about the brain dynamics underlying personality characteristics, and whether they are moderated by age.
methodsWe investigated the associations between personality and resting-state functional MRI data from 365 individuals across the adult lifespan (20-80 years). Participants completed the 50-item International Personality Item Pool and a resting-state imaging protocol on a 3T MRI scanner. Within-network connectivity values were computed based on predefined networks. Regression analyzes were conducted in order to investigate personality-connectivity associations, as well as moderation by age. All models controlled for potential confounders (such as age, sex, education, IQ, and the other personality traits).
resultsWe found that openness was positively associated with connectivity in the default-mode network, neuroticism was negatively associated with both the ventral and dorsal attention networks, and agreeableness was negatively associated with the dorsal attention network. In addition, age moderated the association between conscientiousness and the frontoparietal network, indicating that this association become stronger in older age.
conclusionsOur findings demonstrate that personality is associated with brain connectivity, which may contribute to identifying personality profiles that play a role in protection against or risk for age-related brain changes and dementia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.