Evidence map›Paper›PMID 31903698›Full record

ReviewInternational journal of immunogenetics2020

Immunogenetics in stem cell donor registry work: The DKMS example (Part 1).

Alexander H Schmidt, Jürgen Sauter, Daniel M Baier, Jessica Daiss, Andreas Keller, Anja Klussmeier, Thilo Mengling, Gabi Rall, Tobias Riethmüller, Gerhard Schöfl and 16 more

Abstract readReview
In one paragraph

Review in International journal of immunogenetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Should results of HLA haplotype frequency estimations be normalized?International journal of immunogenetics · 2021
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. IndividualFrontiers in immunology · 2021
    Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Alexander H SchmidtDKMS, Tübingen, Germany.ORCID https://orcid.org/0000-0003-0979-5914
Jürgen SauterDKMS, Tübingen, Germany.ORCID https://orcid.org/0000-0001-8485-2945
Daniel M BaierDKMS, Tübingen, Germany.
Jessica DaissDKMS, Tübingen, Germany.
Andreas KellerDKMS, Tübingen, Germany.
Anja KlussmeierDKMS Life Science Lab, Dresden, Germany.
Thilo MenglingDKMS, Tübingen, Germany.
Gabi RallDKMS, Tübingen, Germany.
Tobias RiethmüllerDKMS, Tübingen, Germany.
Gerhard SchöflDKMS Life Science Lab, Dresden, Germany.ORCID https://orcid.org/0000-0003-3000-3205
Ute V SollochDKMS, Tübingen, Germany.
Tigran TorosianFundacja DKMS, Warsaw, Poland.
David MeansDKMS US, New York, NY, USA.
Helen KellyDKMS UK, London, UK.
Latha JagannathanDKMS BMST Foundation India, Bangalore, India.
Patrick PaulDKMS BMST Foundation India, Bangalore, India.
Anette S GianiFundación de Beneficencia Pública DKMS, Santiago, Chile.
Sabine HildebrandDKMS, Tübingen, Germany.
Stephan SchumacherDKMS, Tübingen, Germany.
Jan MarkertDKMS, Tübingen, Germany.
Monika FüsselDKMS Life Science Lab, Dresden, Germany.
Jan A HofmannDKMS, Tübingen, Germany.
Thomas SchäferDKMS Life Science Lab, Dresden, Germany.
Julia PingelDKMS, Tübingen, Germany.
Vinzenz LangeDKMS Life Science Lab, Dresden, Germany.ORCID https://orcid.org/0000-0002-6442-9573
Johannes ScheteligDKMS, Clinical Trials Unit, Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently, stem cell donor registries include more than 35 million potential donors worldwide to provide HLA-matched stem cell products for patients in need of an unrelated donor transplant. DKMS is a leading stem cell donor registry with more than 9 million donors from Germany, Poland, the United States, the United Kingdom, India and Chile. DKMS donors have donated hematopoietic stem cells more than 80,000 times. Many aspects of donor registry work are closely related to topics from immunogenetics or population genetics. In this two-part review article, we describe, analyse and discuss these areas of donor registry work by using the example of DKMS. Part 1 of the review gives a general overview on DKMS and includes typical donor registry activities with special focus on the HLA system: high-throughput HLA typing of potential stem cell donors, HLA haplotype frequencies and resulting matching probabilities, and donor file optimization with regard to HLA diversity.

Indexed as

Hematopoietic Stem Cell TransplantationRegistriesUnrelated DonorsChileGenetics, PopulationGermanyHaplotypesHigh-Throughput Nucleotide SequencingHistocompatibility TestingHLA AntigensHumansImmunogeneticsIndiaPolandUnited KingdomUnited StatesHLA AntigensDKMSdonor registryHLAunrelated hematopoietic stem cell transplantation

Identifiers

PMID31903698
PMCPMC7003907

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.