Evidence map›Paper›PMID 31903510›Full record

ArticleClinical and experimental nephrology2020

Clinical outcomes after percutaneous coronary intervention in non-dialysis patients with acute coronary syndrome and advanced renal dysfunction.

Yusuke Uemura, Shinji Ishikawa, Kenji Takemoto, Yosuke Negishi, Akihito Tanaka, Kensuke Takagi, Naoyuki Yoshioka, Norio Umemoto, Yosuke Inoue, Itsuro Morishima and 6 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Clinical and experimental nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Yusuke UemuraCardiovascular Center, Anjo Kosei Hospital, 28 Higashi-Hirokute, Anjo, 446-8602, Japan. yusuke0307@kosei.anjo.aichi.jp.ORCID http://orcid.org/0000-0002-2262-1452
Shinji IshikawaCardiovascular Center, Anjo Kosei Hospital, 28 Higashi-Hirokute, Anjo, 446-8602, Japan.
Kenji TakemotoCardiovascular Center, Anjo Kosei Hospital, 28 Higashi-Hirokute, Anjo, 446-8602, Japan.
Yosuke NegishiDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Akihito TanakaDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kensuke TakagiDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Naoyuki YoshiokaDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Norio UmemotoDepartment of Cardiology, Ichinomiya Municipal Hospital, Ichinomiya, Japan.
Yosuke InoueDepartment of Cardiology, Tosei General Hospital, Seto, Japan.
Itsuro MorishimaDepartment of Cardiology, Ogaki Municipal Hospital, Ogaki, Japan.
Naoki ShibataDepartment of Cardiology, Ichinomiya Municipal Hospital, Ichinomiya, Japan.
Hiroshi AsanoDepartment of Cardiology, Tosei General Hospital, Seto, Japan.
Hideki IshiiDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Masato WataraiCardiovascular Center, Anjo Kosei Hospital, 28 Higashi-Hirokute, Anjo, 446-8602, Japan.
Toyoaki MuroharaDepartment of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
N-registry investigators
Anjo Kosei Hospital · JPIchinomiya Municipal City Hospital · JPOgaki Municipal Hospital · JPNagoya University · JPTosei General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundData about the clinical outcomes of ACS patients with advanced renal dysfunction (estimated glomerular filtration rate < 30 mL/min/1.73 m

methodsWe examined the data obtained from 194 ACS patients with non-dialysis advanced renal dysfunction who underwent PCI at five hospitals. The primary composite endpoint was the incidence of major adverse cardiac and cerebrovascular events (MACCE: all-cause death, myocardial infarction, and ischemic stroke).

resultsEighty patients (41.2%) were diagnosed with ST-elevation myocardial infarction (STEMI), and 117 patients (58.8%) with non-ST-elevation ACS (NSTE-ACS). Overall patients were followed for a median of 657.5 days. Cumulative incidence of MACCE at median follow-up was 32.3% (45.4% for STEMI and 23.4% for NSTE-ACS). Kaplan-Meier analysis demonstrated that patients in the STEMI group had significantly higher incidence of MACCE than those in the non-STEMI and unstable angina group (Log-rank p < 0.001). In-hospital MACCE rate was higher in the STEMI group than in the NSTE-ACS group, whereas post-discharge MACCE rate was comparable between the two groups. In the multivariate analysis, STEMI and Killip classification ≥ 2 were associated with in-hospital MACCE. On the other hand, body mass index and serum albumin at admission were independent predictors of post-discharge MACCE.

conclusionsShort- and long-term prognoses following PCI in non-dialysis patients with ACS and advanced renal dysfunction is still unfavorable. STEMI and Killip classification ≥ 2 were independent predictors for in-hospital MACCE, and body mass index and serum albumin were for post-discharge MACCE.

Indexed as

RegistriesAcute Coronary SyndromeAgedAged, 80 and overFemaleHospital MortalityHumansJapanMalePercutaneous Coronary InterventionRenal InsufficiencyRetrospective StudiesAcute coronary syndromeAdvanced renal dysfunctionPrognosis

Identifiers

PMID31903510
OpenAlexW2997930560

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.