Evidence map›Paper›PMID 31903444›Full record

ArticleIEEE transactions on radiation and plasma medical sciences2019

Treatment Outcome Prediction for Cancer Patients based on Radiomics and Belief Function Theory.

Jian Wu, Chunfeng Lian, Su Ruan, Thomas R Mazur, Sasa Mutic, Mark A Anastasio, Perry W Grigsby, Pierre Vera, Hua Li

Abstract read
In one paragraph

Article in IEEE transactions on radiation and plasma medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Semiquantitative 2-[Frontiers in medicine · 2024
    Review
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  4. Improved Prognosis of Treatment Failure in Cervical Cancer with Nontumor PET/CT Radiomics.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jian WuDepartment of Radiation Oncology, Washington University, Saint louis, MO 63110 USA.
Chunfeng LianLaboratoire LITIS (EA 4108), Equipe Quantif, University of Rouen, France.
Su RuanLaboratoire LITIS (EA 4108), Equipe Quantif, University of Rouen, France.
Thomas R MazurDepartment of Radiation Oncology, Washington University, Saint louis, MO 63110 USA.
Sasa MuticDepartment of Radiation Oncology, Washington University, Saint louis, MO 63110 USA.
Mark A AnastasioDepartment of Biomedical Engineering, Washington University, Saint louis, MO 63110 USA.
Perry W GrigsbyDepartment of Radiation Oncology, Washington University, Saint louis, MO 63110 USA.
Pierre VeraLaboratoire LITIS (EA 4108), Equipe Quantif, University of Rouen, France.
Hua LiDepartment of Radiation Oncology, Washington University, Saint louis, MO 63110 USA.

Funding

Multimodal Biomarkers For Oropharyngeal CancerR01CA233873 · NCI · WASHINGTON UNIVERSITY · PI LI, HUA · 2019 to 2024
$2.0M
RADIOMICS-BASED PROGNOSTIC MODEL OF CERVICAL CANCER HABITATSR21CA223799 · NCI · WASHINGTON UNIVERSITY · PI GRIGSBY, PERRY WAYNE, LI, HUA · 2018 to 2019
$368k
NCI NIH HHS R01 CA233873NCI NIH HHS R21 CA223799
6 · The paper itself

Abstract

In this study, we proposed a new radiomics-based treatment outcome prediction model for cancer patients. The prediction model is developed based on belief function theory (BFT) and sparsity learning to address the challenges of redundancy, heterogeneity, and uncertainty of radiomic features, and relatively small-sized and unbalanced training samples. The model first selects the most predictive feature subsets from relatively large amounts of radiomic features extracted from pre- and/or in-treatment positron emission tomography (PET) images and available clinical and demographic features. Then an evidential k-nearest neighbor (EK-NN) classifier is proposed to utilize the selected features for treatment outcome prediction. Twenty-five stage II-III lung, 36 esophagus, 63 stage II-III cervix, and 45 lymphoma cancer patient cases were included in this retrospective study. Performance and robustness of the proposed model were assessed with measures of feature selection stability, outcome prediction accuracy, and receiver operating characteristics (ROC) analysis. Comparison with other methods were conducted to demonstrate the feasibility and superior performance of the proposed model.

Indexed as

Belief Function Theory (BFT)Cancer therapyPET imagesRadiomicsTreatment outcome prediction

Identifiers

PMID31903444
PMCPMC6941853

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.