Evidence map›Paper›PMID 31903430›Full record

ArticleEuropean stroke journal2019

Antibiotic treatment for pneumonia complicating stroke: Recommendations from the pneumonia in stroke consensus (PISCES) group.

Amit K Kishore, Adam R Jeans, Javier Garau, Alejandro Bustamante, Lalit Kalra, Peter Langhorne, Angel Chamorro, Xabier Urra, Mira Katan, Mario Di Napoli and 8 more

Open access · bronzeAbstract read
In one paragraph

Article in European stroke journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

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  12. Role of the gut microbiota in complications after ischemic stroke.Frontiers in cellular and infection microbiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 12 institutions in 6 countries.

Amit K KishoreGreater Manchester Comprehensive Stroke Centre, Manchester Academic Health Science Centre, Salford Royal Foundation Trust, UK.ORCID https://orcid.org/0000-0003-1820-8697
Adam R JeansCentre for Biostatistics, University of Manchester, Salford Royal Foundation Trust, UK.
Javier GarauDepartment of Medicine, Hospital Universitari Mutua de Terrassa, Barcelona, Clinica Rotger Quironsalud, Palma of Mallorca, Spain.
Alejandro BustamanteNeurovascular Research Lab, Vall d'Hebron Research Institute, Barcelona, Spain, Spain.
Lalit KalraClinical Neurosciences, King's College Hospital NHS Foundation Trust, London, UK.
Peter LanghorneInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Angel ChamorroComprehensive Stroke Center, Department of Neuroscience, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Xabier UrraComprehensive Stroke Center, Department of Neuroscience, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Mira KatanDepartment of Neurology, Stroke Center, University Hospital of Zurich, Zurich, Switzerland.
Mario Di NapoliStroke Unit, San Camillo de' Lellis General Hospital, Rieti, Italy.
Willeke WestendorpAmsterdam UMC, University of Amsterdam, Department of Neurology, Amsterdam Neuroscience, Meibergdreef, Amsterdam, Netherlands.
Paul J NederkoornAmsterdam UMC, University of Amsterdam, Department of Neurology, Amsterdam Neuroscience, Meibergdreef, Amsterdam, Netherlands.
Diederik van de BeekAmsterdam UMC, University of Amsterdam, Department of Neurology, Amsterdam Neuroscience, Meibergdreef, Amsterdam, Netherlands.
Christine RoffeKeele University Institute for Science and Technology in Medicine, Guy Hilton Research Centre, Stoke-on-Trent, UK.
Mark WoodheadFaculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Joan MontanerNeurovascular Research Lab, Vall d'Hebron Research Institute, Barcelona, Spain, Spain.
Andreas MeiselNeuroCure Clinical Research Center, Center for Stroke Research Berlin, Department of Neurology, Charité Universitaetsmedizin Berlin, Germany.
Craig J SmithGreater Manchester Comprehensive Stroke Centre, Manchester Academic Health Science Centre, Salford Royal Foundation Trust, UK.
Amsterdam Neuroscience · NLManchester Academic Health Science Centre · GBNeurosciences Institute · USVall d'Hebron Institut de Recerca · ESCharité - Universitätsmedizin Berlin · DEClinica Rotger · ESEllis Hospital · USKeele University · GBKing's College Hospital NHS Foundation Trust · GBSalford Royal NHS Foundation Trust · GBUniversity Hospital of Zurich · CHUniversity of Glasgow · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe microbiological aetiology of pneumonia complicating stroke is poorly characterised. In this second Pneumonia in Stroke ConsEnsuS statement, we propose a standardised approach to empirical antibiotic therapy in pneumonia complicating stroke, based on likely microbiological aetiology, to improve antibiotic stewardship.

methodsSystematic literature searches of multiple databases were undertaken. An evidence review and a round of consensus consultation were completed prior to a final multi-disciplinary consensus meeting in September 2017, held in Barcelona, Spain. Consensus was approached using a modified Delphi technique and defined a priori as 75% agreement between the consensus group members. DISCUSSION: Consensus recommendations for antibiotic treatment of the spectrum of pneumonia complicating stroke are proposed. However, there was limited evidence available to formulate consensus on choice of specific antibiotic class for pneumonia complicating stroke.

conclusionFurther studies are required to inform evidence-based treatment of stroke-associated pneumonia including randomised trials of antibiotics and validation of candidate biomarkers.

Indexed as

antibioticspost-stroke pneumoniaStrokestroke-associated pneumoniatreatment

Identifiers

PMID31903430
PMCPMC6921946
OpenAlexW2943797999

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.