ReviewJournal of thoracic disease2019
Infective endocarditis: trends, surgical outcomes, and controversies.
Review in Journal of thoracic disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Immunosuppressant Use in Infective Endocarditis-Associated Glomerulonephritis: A Systematic Review.Clinical drug investigation · 2025Pooled it
- Antibiotic prophylaxis for preventing bacterial endocarditis following dental procedures.The Cochrane database of systematic reviews · 2022Pooled it
- The influence of the IKAP nursing model on wound healing following vacuum sealing drainage in acute infective endocarditis: a retrospective study.Frontiers in cardiovascular medicine · 2026Article
- Characteristics of patients with infective endocarditis undergoing surgery: a retrospective case series from Vietnam.Open medicine (Warsaw, Poland) · 2026Article
- Trends in Surgery for Endocarditis: 15-Year Experience From a Statewide Quality Collaborative.Annals of thoracic surgery short reports · 2025Article
- Article
- Common Bacterial Infections in Persons Who Inject Drugs.Medicines (Basel, Switzerland) · 2025Review
- Association of socioeconomic disadvantage with operative outcomes for infective endocarditis.PloS one · 2025Article
- The rising cost of infective endocarditis in West Virginia.Epidemiology and infection · 2024Article
- Article
- Longitudinal Outcomes Following Mitral Valve Repair for Infective Endocarditis.Microorganisms · 2024Article
- Kocuria kristinae-Induced Infective Endocarditis: Unveiling an Emerging Threat in Clinical Practice.Cureus · 2024Article
- Article
- Article
- Trends in Infective Endocarditis Mortality in the United States: 1999 to 2020: A Cause for Alarm.Journal of the American Heart Association · 2023Article
- Infective Endocarditis Presenting With Non-ST Elevation Myocardial Infarction: A Case Report.Cureus · 2023Article
- Surgeons' Perspectives on Valve Surgery in People With Drug Use-Associated Infective Endocarditis.The Annals of thoracic surgery · 2023Article
- Comparison of valvuloplasty and replacement for surgical treatment of tricuspid infective endocarditis.BMC cardiovascular disorders · 2023Article
- Effect of intraoperative haemoadsorption therapy on cardiac surgery for active infective endocarditis with confirmed Staphylococcus aureus bacteraemia.Interdisciplinary cardiovascular and thoracic surgery · 2023Article
- Characterization of patients receiving surgical versus non-surgical treatment for infective endocarditis in West Virginia.PloS one · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The number of hospitalizations and surgical cases of infective endocarditis (IE) are increasing. The aim of this study was to review these trends, surgical outcomes, and controversies related to IE. A search of MEDLINE of studies published between 1960 and 2018 was conducted. Search terms included "infective endocarditis", "history of", "trend", "epidemiology", "outcome", "medical management", "surgery", "indication", and "re-operative surgery", or any combination thereof. The United States has the highest incidence of IE in the world at 15 per 100,000 people, with increases in incidence due to the aging population as well as increasing rates of intravenous drug use (IVDU). National guidelines support early surgical intervention in specific clinical settings in both left and right-sided IE. However, only 11% of the evidence used in formulating guidelines for surgical therapy in IE are based on level A evidence. Ongoing controversies include whether to perform surgery in the setting of continued or recurrent IVDU in a patient with a prior valve operation, timing of surgery after acute stroke due to IE, and general indications for surgery for tricuspid valve IE. IE has a surging incidence and increasing burden on the healthcare system in the United States. Multiple controversies exist, and formulating level A evidence and multidisciplinary collaboration will be essential components to effectively treating this complex patient population.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.