Evidence map›Paper›PMID 31903190›Full record

ArticleCanadian journal of kidney health and disease2019

Cultivating Innovative Pragmatic Cluster-Randomized Registry Trials Embedded in Hemodialysis Care: Workshop Proceedings From 2018.

Elliot J Lee, Aakil Patel, Rey R Acedillo, Jovina C Bachynski, Ian Barrett, Erika Basile, Marisa Battistella, Derek Benjamin, David Berry, Peter G Blake and 49 more

Open access · goldAbstract read
In one paragraph

Article in Canadian journal of kidney health and disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

59 authors at 20 institutions in 3 countries.

Elliot J LeeICES, ON, Canada.ORCID https://orcid.org/0000-0001-9320-195X
Aakil PatelICES, ON, Canada.
Rey R AcedilloDivision of Nephrology, Department of Medicine, London Health Sciences Centre, ON, Canada.
Jovina C BachynskiHalton Healthcare Services, Oakville, ON, Canada.
Ian BarrettSt. Michael's Hospital, Toronto, ON, Canada.
Erika BasileOffice of Human Research Ethics, Western University, London, ON, Canada.
Marisa BattistellaDepartment of Pharmacy, University Health Network, Toronto, ON, Canada.
Derek BenjaminRoyal Victoria Regional Health Centre, Barrie, ON, Canada.
David BerryAlgoma Regional Renal Program, Sault Area Hospital, Sault Ste. Marie, ON, Canada.
Peter G BlakeDivision of Nephrology, Department of Medicine, London Health Sciences Centre, ON, Canada.
Patricia ChanDivision of Nephrology, Department of Medicine, Michael Garron Hospital, Toronto, ON, Canada.
Clara J BohmDepartment of Internal Medicine, Max Rady College of Medicine, University of Manitoba, Winnipeg, Canada.
Kristin K ClemensICES, ON, Canada.
Charles CookTransplant Ambassador Program, Grand River Hospital, Kitchener, ON, Canada.
Laura DemberRenal, Electrolyte and Hypertension Division, Perelman School of Medicine, Philadelphia, PA, USA.
Jade S DirkICES, ON, Canada.
Stephanie DixonICES, ON, Canada.
Elisabeth FowlerThe Kidney Foundation of Canada, Montreal, QC, Canada.
Leah GetchellCan-SOLVE CKD Network, Vancouver, BC, Canada.
Nazanine GholamiSt. Joseph's Health Centre, Toronto, ON, Canada.
Cory GoldsteinRotman Institute of Philosophy, Western University, London, ON, Canada.
Emma HahnICES, ON, Canada.
Betty HogeterpLakeridge Health Oshawa, ON, Canada.
Susan HuangDivision of Nephrology, Department of Medicine, London Health Sciences Centre, ON, Canada.
Michelle HughesOrillia Soldiers' Memorial Hospital, ON, Canada.
Meg J JardineInnovation & Kidney Research, The George Institute for Global Health, UNSW Sydney, Newtown, NSW, Australia.
Shasikara KalatharanCan-SOLVE CKD Network, Vancouver, BC, Canada.
Shane KilburnICES, ON, Canada.
Eduardo LacsonTufts Medical Center, Boston, MA, USA.
Sean LeonardICES, ON, Canada.
Channing LibertyThe Ottawa Hospital, ON, Canada.
Craig LindsayScarborough Health Network, Toronto, ON, Canada.
Jennifer M MacRaeDivision of Nephrology, Department of Medicine, University of Calgary, AB, Canada.
Braden J MannsDepartment of Medicine, Cumming School of Medicine, University of Calgary, AB, Canada.ORCID https://orcid.org/0000-0002-8823-6127
Janice McCallumOntario Renal Network, Cancer Care Ontario, Toronto, Canada.
Christopher W McIntyreKidney Clinical Research Unit, Lawson Health Research Institute, London, ON, Canada.
Amber O MolnarICES, ON, Canada.ORCID https://orcid.org/0000-0003-4549-0202
Reem A MustafaDivision of Nephrology and Hypertension, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, USA.
Gihad E NesrallahDivision of Nephrology, Department of Medicine, Humber River Hospital, Toronto, ON, Canada.
Matthew J OliverDivision of Nephrology, Department of Medicine, University of Toronto, ON, Canada.
Michael PandesMackenzie Health, Richmond Hill, ON, Canada.
Sanjay PandeyaHalton Healthcare, Oakville, ON, Canada.
Malvinder S ParmarKidney Care Centre, Timmins and District Hospital, ON, Canada.
Elijah Z RabinNiagara Health System, St. Catharines, ON, Canada.
Johnathan RileyOntario SPOR SUPPORT Unit, Toronto, ON, Canada.
Samuel A SilverDivision of Nephrology, Kingston Health Sciences Center, Queen's University, Kingston, ON, Canada.
Jessica M SontropICES, ON, Canada.
Manish M SoodICES, ON, Canada.ORCID https://orcid.org/0000-0002-9146-2344
Rita S SuriDivision of Nephrology, Department of Medicine, McGill University, Montreal, QC, Canada.
Navdeep TangriChronic Disease Innovation Centre, Winnipeg, MB, Canada.
Daniel J TasconaOntario Renal Network, Cancer Care Ontario, Toronto, Canada.
Alison ThomasSt. Michael's Hospital, Toronto, ON, Canada.
Ron WaldSt. Michael's Hospital, Toronto, ON, Canada.ORCID https://orcid.org/0000-0003-4411-8169
Michael WalshDivision of Nephrology, Department of Medicine, McMaster University, Hamilton, ON, Canada.
Charles WeijerDepartment of Epidemiology and Biostatistics, Western University, London, ON, Canada.
Matthew A WeirICES, ON, Canada.
Hans VorsterOntario Renal Network, Cancer Care Ontario, Toronto, Canada.
Deborah ZimmermanDivision of Nephrology, Department of Medicine, University of Ottawa, ON, Canada.
Western University · CACancer Care Ontario · CASt. Michael's Hospital · CAHalTech · CALawson Health Research Institute · CAUniversity of Calgary · CAUniversity of Ottawa · CACanadian Society of Nephrology · CAGrand River Hospital · CAHumber River Regional Hospital · CAKidney Foundation of Canada · CALakeridge Health · CALondon Health Sciences Centre · CAMcMaster University · CANiagara Health System · CAOrthopaedic Innovation Centre · CAOttawa Hospital · CAPopulation Health Research Institute · CAQueen's University · CARoyal Victoria Regional Health Centre · CA

Funding

Pragmatic Trials in Maintenance HemodialysisUH3DK102384 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI DEMBER, LAURA M · 2013 to 2016
$5.8M
NIDDK NIH HHS UH3 DK102384
6 · The paper itself

Abstract

Hemodialysis is a life-sustaining treatment for persons with kidney failure. However, those on hemodialysis still face a poor quality of life and a short life expectancy. High-quality research evidence from large randomized controlled trials is needed to identify interventions that improve the experiences, outcomes, and health care of persons receiving hemodialysis. With the support of the Canadian Institutes of Health Research and its Strategy for Patient-Oriented Research, the Innovative Clinical Trials in Hemodialysis Centers initiative brought together Canadian and international kidney researchers, patients, health care providers, and health administrators to participate in a workshop held in Toronto, Canada, on June 2 and 3, 2018. The workshop served to increase knowledge and awareness about the conduct of innovative, pragmatic, cluster-randomized registry trials embedded into routine hemodialysis care and provided an opportunity to discuss and build support for new trial ideas. The workshop content included structured presentations, facilitated group discussions, and expert panel feedback. Partnerships and promising trial ideas borne out of the workshop will continue to be developed to support the implementation of future large-scale trials.

Indexed as

chronic kidney diseasecluster randomizedhemodialysispatient-oriented researchpragmaticrandomized controlled trialregistry-basedworkshop

Identifiers

PMID31903190
PMCPMC6933546
OpenAlexW2997496272

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.