Evidence map›Paper›PMID 31903128›Full record

ArticleTheranostics2020

PET/MRI enables simultaneous

Filippo C Michelotti, Gregory Bowden, Astrid Küppers, Lieke Joosten, Jonas Maczewsky, Volker Nischwitz, Gisela Drews, Andreas Maurer, Martin Gotthardt, Andreas M Schmid and 1 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. New Long-Acting [Journal of medicinal chemistry · 2023
    Article
  6. Article
  7. Article
  8. Imaging Techniques in Pharmacological Precision Medicine.Handbook of experimental pharmacology · 2023
    Article
  9. Impact of anFrontiers in endocrinology · 2023
    Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Beta Cell Imaging-From Pre-Clinical Validation to First in Man Testing.International journal of molecular sciences · 2020
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Filippo C MichelottiWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.
Gregory BowdenWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.
Astrid KüppersForschungszentrum Jülich GmbH, Central Institute of Engineering, Electronics and Analytics, Jülich, Germany.
Lieke JoostenRadboud University Medical Center, Department of Radiology and Nuclear Medicine, Nijmegen, The Netherlands.
Jonas MaczewskyExperimental Diabetology, Phamacology, Pharmaceutical Institute, Eberhard Karls University Tübingen, Tübingen, Germany.
Volker NischwitzForschungszentrum Jülich GmbH, Central Institute of Engineering, Electronics and Analytics, Jülich, Germany.
Gisela DrewsExperimental Diabetology, Phamacology, Pharmaceutical Institute, Eberhard Karls University Tübingen, Tübingen, Germany.
Andreas MaurerWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.
Martin GotthardtRadboud University Medical Center, Department of Radiology and Nuclear Medicine, Nijmegen, The Netherlands.
Andreas M SchmidWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.
Bernd J PichlerWerner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen, Tübingen, Germany.
Forschungszentrum Jülich · DESiemens (Germany) · DEUniversity of Tübingen · DERadboud University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-invasive imaging of β-cells represents a desirable preclinical and clinical tool to monitor the change of β-cell mass and the loss of function during pre-diabetic stages. Although it is widely accepted that manganese (Mn) ions are actively gated by voltage-dependent calcium channels (VDCC) in response to glucose metabolism, little is known on its specificity

Indexed as

Insulin-Secreting CellsMagnetic Resonance ImagingPancreasPositron-Emission TomographyAnimalsCalcium ChannelsGlucagon-Like Peptide-1 ReceptorManganeseMiceMice, TransgenicPancreatic NeoplasmsRadiopharmaceuticalsCalcium ChannelsGlp1r protein, mouseGlucagon-Like Peptide-1 ReceptorManganeseRadiopharmaceuticalsGLP-1R.MRIPETPET/MRIVDCCβ-cell functionβ-cell mass

Identifiers

PMID31903128
PMCPMC6929626
OpenAlexW2984001329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.