Evidence map›Paper›PMID 31903127›Full record

ArticleTheranostics2020

Bax inhibitor 1 preserves mitochondrial homeostasis in acute kidney injury through promoting mitochondrial retention of PHB2.

Jin Wang, Pingjun Zhu, Ruibing Li, Jun Ren, Yingmei Zhang, Hao Zhou

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 90 papers.

0numbers the graph read from it
0cells of the map it votes in
90citing papers in PubMed
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

90 citing papers in PubMed, 133 citations in OpenAlex.

  1. Article
  2. Review
  3. Mitophagy in kidney transplantation ischemia-reperfusion injury.International urology and nephrology · 2026
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  17. Review
  18. Mitophagy in renal interstitial fibrosis.International urology and nephrology · 2024
    Review
  19. Article
  20. Article

30 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Jin WangChinese PLA General Hospital, Medical School of Chinese PLA, Beijing, 100853, China.
Pingjun ZhuChinese PLA General Hospital, Medical School of Chinese PLA, Beijing, 100853, China.
Ruibing LiChinese PLA General Hospital, Medical School of Chinese PLA, Beijing, 100853, China.
Jun RenCenter for Cardiovascular Research and Alternative Medicine, University of Wyoming College of Health Sciences, Laramie, WY 82071 USA.
Yingmei ZhangCenter for Cardiovascular Research and Alternative Medicine, University of Wyoming College of Health Sciences, Laramie, WY 82071 USA.
Hao ZhouChinese PLA General Hospital, Medical School of Chinese PLA, Beijing, 100853, China.
Chinese PLA General Hospital · CNUniversity of Wyoming · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bax inhibitor-1 (BI1) conveys anti-apoptotic signals for mitochondria while prohibitin 2 (PHB2) is implicated in sustaining mitochondrial morphology and function. However, their regulatory roles in acute kidney injury (AKI) are largely unknown.

Indexed as

Apoptosis Regulatory ProteinsMembrane ProteinsAcute Kidney InjuryAnimalsApoptosisCell LineHumansKidney Tubules, ProximalMiceMice, Inbred C57BLMice, TransgenicMitochondriaMitochondrial DynamicsOxidative StressProhibitinsRepressor ProteinsApoptosis Regulatory ProteinsMembrane ProteinsPHB2 protein, humanPhb2 protein, mousePHB protein, humanProhibitinsRepressor ProteinsTMBIM6 protein, humanTmbim6 protein, mouseAKIBI1mitochondriaPHB2.tubule cells

Identifiers

PMID31903127
PMCPMC6929616
OpenAlexW2986558453

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.