Evidence map›Paper›PMID 31903114›Full record

ArticleTheranostics2020

Coniferaldehyde attenuates Alzheimer's pathology

Yaqiong Dong, Tessandra Stewart, Lidan Bai, Xue Li, Ting Xu, Jeffrey Iliff, Min Shi, Danfeng Zheng, Lan Yuan, Taotao Wei and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 59 citations in OpenAlex.

  1. Article
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  7. Macadamia (Foods (Basel, Switzerland) · 2024
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  9. Review
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  12. Neurotrophic Natural Products.Progress in the chemistry of organic natural products · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Yaqiong DongThe State Key Laboratories of Natural and Biomimetic Drugs and Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
Tessandra StewartDepartment of Pathology, University of Washington School of Medicine, Seattle, WA 98104, United States.
Lidan BaiThe State Key Laboratories of Natural and Biomimetic Drugs and Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
Xue LiThe State Key Laboratories of Natural and Biomimetic Drugs and Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
Ting XuThe State Key Laboratories of Natural and Biomimetic Drugs and Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
Jeffrey IliffDepartment of Anesthesiology and Perioperative Medicine, Knight Cardiovascular Institute, Oregon Health & Science University, Portland, OR, United States.
Min ShiDepartment of Pathology, University of Washington School of Medicine, Seattle, WA 98104, United States.
Danfeng ZhengDepartment of Pathology, School of Basic Medical Sciences, Peking University Health Science Center, Beijing 100191, China.
Lan YuanThe State Key Laboratories of Natural and Biomimetic Drugs and Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
Taotao WeiNational Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Xiaoda YangThe State Key Laboratories of Natural and Biomimetic Drugs and Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing 100191, China.
Jing ZhangDepartment of Pathology, University of Washington School of Medicine, Seattle, WA 98104, United States.
Peking University · CNUniversity of Washington · USInstitute of Biophysics · CNOregon Health & Science University · US

Funding

Peptide Biomarkers for Alzheimer DiseaseR01AG056711 · NIA · UNIVERSITY OF WASHINGTON · PI SHI, MIN · 2017 to 2021
$4.1M
Defining the role of age-related glymphatic pathway impairment in amyloid beta plaque depositionR01AG054456 · NIA · SEATTLE INST FOR BIOMEDICAL/CLINICAL RES · PI ILIFF, JEFFREY J · 2017 to 2021
$1.8M
Role of perivascular aquaporin-4 polarization in post-traumatic neurodegenerationR01NS089709 · NINDS · SEATTLE INST FOR BIOMEDICAL/CLINICAL RES · PI ILIFF, JEFFREY J · 2015 to 2019
$1.7M
NIA NIH HHS R01 AG054456NIA NIH HHS R01 AG056711NINDS NIH HHS R01 NS089709
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AcroleinAlzheimer DiseaseAmyloid beta-PeptidesAnimalsBrainCell Line, TumorFemaleHumansMaleMice, Inbred C57BLMice, TransgenicNeuronsNeuroprotective AgentsNF-E2-Related Factor 2AcroleinAmyloid beta-PeptidesconiferaldehydeNeuroprotective AgentsNFE2L2 protein, humanNfe2l2 protein, mouseNF-E2-Related Factor 2Alzheimer's diseaseAβ clearanceconiferaldehydeneuroprotectionNrf2

Identifiers

PMID31903114
PMCPMC6929631
OpenAlexW2982526781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.