Evidence map›Paper›PMID 31902329›Full record

ArticleJournal of the American Heart Association2020

Progression of Arterial Stiffness is Associated With Midlife Diastolic Blood Pressure and Transition to Late-Life Hypertensive Phenotypes.

Alastair John Stewart Webb

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Consistency of associations of systolic and diastolic blood pressure with white matter hyperintensities: A meta-analysis.International journal of stroke : official journal of the International Stroke Society · 2022
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Characteristics and Determinants of Pulse Wave Velocity in Super Normal Vascular Aging (SUPERNOVA) Patients.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Article
  5. The vascular contribution to dementia: World Stroke Organization scientific statement.International journal of stroke : official journal of the International Stroke Society · 2026
    Review
  6. The role of impaired autoregulation in cerebral small vessel disease and vascular cognitive impairment.International journal of stroke : official journal of the International Stroke Society · 2026
    Review
  7. Review
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  14. Temporal relationship between arterial stiffness and blood pressure variability and joint effect on cardiovascular disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  15. Article
  16. Article
  17. Vascular phenotypes in early hypertension.Journal of human hypertension · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Alastair John Stewart WebbWolfson Centre for Prevention of Stroke and Dementia University of Oxford United Kingdom.

Funding

British Heart Foundation PG/16/38/32080Medical Research Council MC_PC_12028Medical Research Council MC_PC_17228Medical Research Council MC_QA137853Wellcome Trust 206589/Z/17/Z
6 · The paper itself

Abstract

Background Hypertension-associated cardiovascular events are particularly associated with elevated systolic blood pressure (SBP) in late life, yet long-term interactions between SBP, diastolic BP (DBP) and arterial stiffness in development of late-life hypertensive phenotypes remain unclear. Methods and Results In the UK Biobank, we determined associations between arterial stiffness index (ASI), SBP, DBP, and their progression, and transition from normotension (<140/90 mm Hg) to hypertension or elevated ASI (>10 m/s). Associations were determined by general linear and logistic regression, adjusted for cardiovascular risk factors and variability of measurements across follow-ups. Mean values of baseline SBP, DBP, and ASI were determined stratified by deciles of age, blood pressure, and ASI, with CIs determined by bootstrapping. In 169 742 participants at baseline, ASI was more strongly associated with DBP than SBP, before and after adjustment for risk factors (β: SBP, -0.01 [

Indexed as

Arterial PressureVascular StiffnessAdultAgedAge FactorsCross-Sectional StudiesDisease ProgressionFemaleHumansHypertensionLongitudinal StudiesMaleMiddle AgedPhenotypeRisk AssessmentRisk Factorsarterial stiffnesshypertensionlongitudinal cohort study

Identifiers

PMID31902329
PMCPMC6988142

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.