ArticleThe Journal of asthma : official journal of the Association for the Care of Asthma2021
Incidence of supraventricular tachycardia after inhaled short-acting beta agonist treatment in children.
Article in The Journal of asthma : official journal of the Association for the Care of Asthma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Safety outcomes of salbutamol: A systematic review and meta-analysis.The clinical respiratory journal · 2023Pooled it
- Cardiovascular Implications of the Enhanced Games: Performance Enhancing Drugs in Competition and Recreation.Sports medicine - open · 2026Review
- A quality improvement initiative to reduce excess inhaled therapy use in the neonatal intensive care unit.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Bind: large-scale biological interaction network discovery through knowledge graph-driven machine learning.Journal of translational medicine · 2025Article
- Supraventricular tachycardia diagnosis in asthma patients is associated with adverse health outcomes.Pediatric pulmonology · 2024Article
- Critical reappraisal of short-acting bronchodilators for pediatric respiratory diseases.Italian journal of pediatrics · 2024Review
- Drugs associated with a risk of supraventricular tachycardia: analysis using the OpenVigil database.The Journal of international medical research · 2024Article
- Asthma and COPD: A Focus on β-Agonists - Past, Present and Future.Handbook of experimental pharmacology · 2024Review
- Inhaled Short-Acting Beta Agonist Treatment-Associated Supraventricular Tachycardia in Children: Still a Matter of Concern in Pediatric Emergency Departments?Children (Basel, Switzerland) · 2023Article
- Effect of inhaled albuterol on whole blood potassium concentrations in dogs.Journal of veterinary internal medicine · 2022Article
- Effect of asthma and asthma medication on the prognosis of patients with COVID-19.The European respiratory journal · 2021Article
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
Abstract
introductionAlbuterol can trigger supraventricular tachycardia (SVT). The clinical characteristics, incidence, and risk factors of SVT after inhaled SABA treatment in children are currently unknown. Through review of regional care delivery, we will describe cases of SVT during asthma treatment in hospital-based settings, define the incidence of SVT in our population, and evaluate risk factors of SABA-induced SVT.
methodsWe identified hospital-based care episodes of children 0-18 years old between 2006 and 2015 recorded in the Intermountain Healthcare EDW with either 1) diagnosis codes for both asthma and SVT or 2) both SABA and adenosine listed as billed medications. Controls were matched with cases by age and sex to determine risk factors for SVT after SABA using conditional logistic regression.
resultsOf 93 care episodes meeting criteria, we found 7 cases of SVT after SABA treatment in 6 patients over 10 years. In our population, the incidence of SVT is 3.9 per 10,000 episodes of SABA treatment, and 5.1 per 10,000 children with asthma receiving hospital-based asthma care. Two episodes of SVT followed treatment with only levalbuterol, three after only albuterol, and two after both albuterol and levalbuterol treatment. Five cases of SVT were converted to sinus rhythm with adenosine, one converted with synchronized electrical cardioversion, and one resolved spontaneously. No cases of SVT led to death. No examined variables were associated with SABA-induced SVT.
conclusionsSVT is rare during hospital-based treatment for acute asthma using inhaled SABAs and has low morbidity and mortality.
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