ArticleKorean journal of family medicine2020
Association of Thyroid Status with Health-Related Quality of Life in Korean Older Adults.
Article in Korean journal of family medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Investigating the relationship between thyroid replacement therapy goals status and quality of life in patients with primary hypothyroidism.Endocrine · 2026Article
- Cost-Effectiveness of Proton Versus Photon Therapy for Medulloblastoma Using Updated Clinical Outcomes.International journal of particle therapy · 2025Article
- Comparison of the Changes in Quality-of-Life of Cats with Hyperthyroidism Treated with Radioiodine or Antithyroid Drugs-A Preliminary Study.Veterinary sciences · 2025Article
- Owners' Experience and Satisfaction with Radioiodine Treatment in Hyperthyroid Cats-A Prospective Questionnaire Study.Veterinary sciences · 2025Article
- Correlation of gender with health related-quality of life of patients in 13 groups of disease in Poland.Scientific reports · 2025Article
- Prevalence and Risk Factors of Subclinical Hypothyroidism in Young and Middle-Aged Patients With First-Episode Drug-Naïve Major Depressive Disorder.Depression and anxiety · 2025Article
- Article
- Assessment of Quality of Life Among Patients With Primary Hypothyroidism: A Case-Control Study.Cureus · 2022Article
- Cost-Effectiveness of Dronedarone and Amiodarone for the Treatment of Chinese Patients With Atrial Fibrillation.Frontiers in public health · 2021Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile hypothyroidism is associated with negative health effects in the general population, older adults with hypothyroidism have better physical function and comparable rates of depression and cognitive impairment relative to their euthyroid counterparts. The aim of this study was to investigate the association between thyroid status and health-related quality of life in Korean older adults.
methodsIn this population-based cross-sectional study, 1,060 adults aged over 60 years were classified by thyroid status into four groups based on their thyroid stimulating hormone (TSH) and free T4 values: overt hypothyroid, subclinical hypothyroid, euthyroid, and subclinical hyperthyroid. The main outcome measure was self-reported health-related quality of life based on the three-level version of the EuroQol-5 dimension (EQ-5D), with utility values of -0.171 and 1.000 corresponding to the worst and best health statuses, respectively. The adjusted means of the EQ-5D three-level version utility values according to thyroid status were determined using a linear regression analysis.
resultsIn the adjusted analysis, the overt hypothyroid group showed significantly higher EQ-5D three-level version utility values than did the euthyroid group (0.998 vs. 0.908, P=0.000). In the subgroup analyses by sex, the overt hypothyroid group also showed significantly higher EQ-5D three-level version utility values for both men and women than did the euthyroid group (0.998 vs. 0.940, P=0.008; 0.983 vs. 0.882, P=0.001).
conclusionAsymptomatic Korean older adults aged over 60 years with TSH and free T4 values corresponding to overt hypothyroidism have better health-related quality of life than their euthyroid counterparts.
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