ReviewDiabetes & metabolism journal2019
Two Faces of White Adipose Tissue with Heterogeneous Adipogenic Progenitors.
Review in Diabetes & metabolism journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
40 citing papers in PubMed, 78 citations in OpenAlex.
- Exploring the transcriptional crosstalk between adipose tissue and locoregional recurrence in breast cancer using independent component analysis.Functional & integrative genomics · 2026Article
- Differential Association of Visceral and Subcutaneous Adipose Tissue with Treatment Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer.Diagnostics (Basel, Switzerland) · 2026Article
- Adipose tissue distribution in metabolic disease: depot-specific biology, clinical assessment, and therapeutic remodeling.Frontiers in endocrinology · 2026Review
- Inhibition of lipolysis in visceral adipose tissue from obese mice and humans prevents impairment of endothelial Kir2.1 channels.Channels (Austin, Tex.) · 2025Article
- The Dual Role of Perivascular Adipose Tissue in Vascular Homeostasis and Atherogenesis: From Physiology to Pathological Implications.International journal of molecular sciences · 2025Review
- β-Hydroxybutyrate Reduces Body Weight by Modulating Fatty Acid Oxidation and Beiging in the Subcutaneous Adipose Tissue of DIO Mice.International journal of molecular sciences · 2025Article
- Prognostic impact of visceral and subcutaneous fat area in stage I-III colon cancer patients with cachexia: a population-based multicenter study.Frontiers in nutrition · 2025Article
- snRNA-seq reveals subcutaneous white adipose tissue remodeling upon return to thermoneutrality after cold stimulation.Frontiers in cell and developmental biology · 2025Article
- Association between cardiometabolic index and all-cause and cause-specific mortality among the general population: NHANES 1999-2018.Lipids in health and disease · 2024Article
- Cinnamon powder intake enhances the effect of caloric restriction on white adipose tissue in male rats.Journal of molecular histology · 2024Article
- The association of obesity and the risk of rheumatoid arthritis according to abdominal obesity status: a nationwide population-based study in Korea.Rheumatology international · 2024Article
- Anti-Obesity Effects ofNutrients · 2024Article
- Dynamics of single-nuclei transcriptomic profiling of adipose tissue from diverse anatomical locations during mouse aging process.Scientific reports · 2024Article
- Visceral adipose of obese mice inhibits endothelial inwardly rectifying KAmerican journal of physiology. Cell physiology · 2024Article
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- Subcutaneous fat predicts bone metastasis in breast cancer: A novel multimodality-based deep learning model.Cancer biomarkers : section A of Disease markers · 2024Article
- Association between abdominal adiposity and clinical outcomes in patients with acute ischemic stroke.PloS one · 2024Article
- Obesity and the risk of cardiometabolic diseases.Nature reviews. Cardiology · 2023Review
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Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic energy surplus increases body fat, leading to obesity. Since obesity is closely associated with most metabolic complications, pathophysiological roles of adipose tissue in obesity have been intensively studied. White adipose tissue is largely divided into subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT). These two white adipose tissues are similar in their appearance and lipid storage functions. Nonetheless, emerging evidence has suggested that SAT and VAT have different characteristics and functional roles in metabolic regulation. It is likely that there are intrinsic differences between VAT and SAT. In diet-induced obese animal models, it has been reported that adipogenic progenitors in VAT rapidly proliferate and differentiate into adipocytes. In obesity, VAT exhibits elevated inflammatory responses, which are less prevalent in SAT. On the other hand, SAT has metabolically beneficial effects. In this review, we introduce recent studies that focus on cellular and molecular components modulating adipogenesis and immune responses in SAT and VAT. Given that these two fat depots show different functions and characteristics depending on the nutritional status, it is feasible to postulate that SAT and VAT have different developmental origins with distinct adipogenic progenitors, which would be a key determining factor for the response and accommodation to metabolic input for energy homeostasis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.