ArticleEnvironmental science and pollution research international2020
Effects of cadmium on the gene transcription of the liver in the freshwater turtle (Chinemys reevesii).
Article in Environmental science and pollution research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 19 citations in OpenAlex.
- Establishment and characterization of turtle liver organoids provides a potential model to decode their unique adaptations.Communications biology · 2024Article
- Biogenic Elements and Heavy Metals in Hermann's Tortoises-Animals : an open access journal from MDPI · 2023Article
- Whole Transcriptome Profiling of the Effects of Cadmium on the Liver of the Xiangxi Yellow Heifer.Frontiers in veterinary science · 2022Article
- Oxidative stress in liver of turtle Mauremys reevesii caused by cadmium.Environmental science and pollution research international · 2021Article
- Lipid peroxidation of kidney of the turtle Mauremys reevesii caused by cadmium.Environmental science and pollution research international · 2021Article
- A First Insight into the Structural and Functional Comparison of Environmental Microbiota in Freshwater TurtleMicroorganisms · 2020Article
- Effects of cadmium on the activities of ALT and AST as well as the content of TP in plasma of freshwater turtle Mauremys reevesii.Environmental science and pollution research international · 2020Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
This study investigated the related gene transcription of liver in freshwater turtle Chinemys reevesii exposed to cadmium (Cd). After acclimation, healthy turtles were selected for experiments. They were randomly divided into four experimental groups and each group had 5 animals. The turtles were treated with 0 mg/kg, 7.5 mg/kg, 15 mg/kg, and 30 mg/kg Cd chloride separately by intraperitoneal injection. Liver samples were collected for examination of the transcription of related genes at 2 weeks after Cd exposure. The transcription of mRNA of MT, SOD, CAT, PNKP, and GPX4 genes in turtle liver cells were analyzed. Results showed that Cd promoted MT mRNA transcription in turtle's liver at low dose (7.5 mg/kg) and inhibited MT mRNA transcription in turtle's liver at middle dose (15 mg/kg) and high dose (30 mg/kg). Cd inhibited the transcription of SOD, CAT, and PNKP mRNA in turtle's liver, and the inhibition was obvious at high dose (30 mg/kg). Cd promoted GPX4 mRNA transcription in turtle's liver, especially at low dose (7.5 mg/kg). In conclusion, Cd had different effects on the mRNA transcription of liver cells in the freshwater turtle Chinemys reevesii exposed to Cd.
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