ArticleJournal of neurology2020
Dynamics of impulsive-compulsive behaviors in early Parkinson's disease: a prospective study.
Article in Journal of neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Pharmacological and non-pharmacological treatments for impulsive-compulsive behaviors in Parkinson's disease.The Cochrane database of systematic reviews · 2025Pooled it
- Risk factors of impulsive-compulsive behaviors in PD patients: a meta-analysis.Journal of neurology · 2022Pooled it
- Caregiver burden of parkinsonian patients with impulse control disorders, depression and apathy.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Gender differences in non-motor symptoms in Parkinson's disease: a multicenter longitudinal study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026Article
- Neuropsychological aspects of impulse control disorders in Parkinson's disease.Frontiers in aging neuroscience · 2026Review
- A transdiagnostic approach to non-motor symptoms in Parkinson's disease: exploring internalizing, bipolar spectrum, and impulsive compulsive behavior profiles via cluster analysis.Frontiers in aging neuroscience · 2026Article
- Is GBA1 mutation status a game-changer for impulse control behaviour in Parkinson's disease?Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Uric Acid and Impulse Control Disorders in Parkinson's Disease: A Cross-Sectional Analysis.Medicina (Kaunas, Lithuania) · 2025Article
- Disordered Eating Behaviors in Individuals With Physical Disabilities: A Narrative Review.American journal of lifestyle medicine · 2025Review
- Psychometric properties of the Italian version of scale for outcomes in Parkinson's disease psychiatric complications in Parkinson disease.Scientific reports · 2025Article
- Behavioral disorders in Parkinson disease: current view.Journal of neural transmission (Vienna, Austria : 1996) · 2025Review
- Neuropsychiatric symptoms in Parkinson's disease: review of data from the Arab world.The Journal of international medical research · 2024Review
- Neurologic comorbidity in psychiatric inpatients: evidence from neurologic consultations in a Spanish center.Revista de neurologia · 2024Article
- Impulse Control Disorders in Parkinson's Disease and Atypical Parkinsonian Syndromes-Is There a Difference?Brain sciences · 2024Article
- Associations of motor and neuropsychiatric symptoms with comorbidities in prodromal Parkinson's disease.Frontiers in aging neuroscience · 2024Article
- Impulse Control Disorders in the Polish Population of Patients with Parkinson's Disease.Medicina (Kaunas, Lithuania) · 2023Article
- Punding in Parkinson's Disease: An Update.Movement disorders clinical practice · 2023Review
- Performance on the balloon analogue risk task and anticipatory response inhibition task is associated with severity of impulse control behaviours in people with Parkinson's disease.Experimental brain research · 2023Article
- Assessing impulse control behaviors in early Parkinson's disease: a longitudinal study.Frontiers in neurology · 2023Article
- The neuropsychiatry of Parkinson's disease: advances and challenges.The Lancet. Neurology · 2022Review
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
introductionImpulsive compulsive behaviors (ICBs) in Parkinson's disease (PD) are debilitating disorders of repetitive, excessive, and compulsive nature affecting up to one third of PD patients. Objectives are to address clinical, psychiatric, and cognitive characteristics of ICBs and to define risk factors in PD patients in the initial motor stage, followed up for 5 years.
methodsWe analyzed 106 consecutive PD outpatients at Hoehn and Yahr disease stage 1 and 125 healthy controls. The participants were assessed for the presence of any ICB using the current clinical criteria and underwent comprehensive clinical, psychiatric, and neuropsychological evaluations. The patients completed the same protocol at Years 1, 2, 3, and 5.
resultsICBs were present in 21 (19.8%) PD patients and 13 (10.4%) healthy controls at baseline. Prevalence of ICBs increased to 29.2% at Year 5, significantly after Year 2. Multiple ICBs were present in 4,7% and 61.9% of PD-ICBs at the baseline and Year 5, respectively. ICBs resolved in 30% of cases (most often compulsive eating). Dopamine agonist treatment at the baseline carried five times higher risk of having or developing ICB(s) anytime during follow-up. We identified risk factors for compulsive eating (dopamine agonist treatment at baseline), hypersexuality (males), compulsive buying (depression and younger age), and punding (younger age and higher levodopa dose at baseline). Significant interaction of rate of motor progression and ICB diagnosis was shown.
conclusionsPD patients showed increasing frequency of most ICBs during the 5-year follow-up. Specific risk factors were identified for different types of ICBs.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.