Evidence map›Paper›PMID 31901995›Full record

ArticleParasitology research2020

First molecular characterization of Sarcocystis neurona causing meningoencephalitis in a domestic cat in Brazil.

Márcia Elisa Hammerschmitt, Luan Cleber Henker, Juliana Lichtler, Fernanda Vieira Amorim da Costa, Rodrigo Martins Soares, Horwald Alexander Bedoya Llano, Saulo Petinatti Pavarini

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Parasitology research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. The Canadian veterinary journal = La revue veterinaire canadienne · 2025
    Article
  2. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
    Article
  3. Molecular identification ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  4. Article
  5. Meningoencephalomyelitis in domestic cats: 3 cases ofJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021
    Review
  6. Article
  7. Reactivity of Horse Sera to Antigens Derived FromFrontiers in veterinary science · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Márcia Elisa HammerschmittSetor de Patologia Veterinária, Departamento de Patologia Clínica, Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Bairro Agronomia, Porto Alegre, RS, 91540-000, Brazil. marciahammer@hotmail.com.ORCID http://orcid.org/0000-0002-4990-5412
Luan Cleber HenkerSetor de Patologia Veterinária, Departamento de Patologia Clínica, Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Bairro Agronomia, Porto Alegre, RS, 91540-000, Brazil.
Juliana LichtlerSetor de Medicina Felina, Hospital de Clínicas Veterinárias, Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Bairro Agronomia, Porto Alegre, RS, 91540-000, Brazil.
Fernanda Vieira Amorim da CostaSetor de Medicina Felina, Hospital de Clínicas Veterinárias, Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Bairro Agronomia, Porto Alegre, RS, 91540-000, Brazil.
Rodrigo Martins SoaresDepartamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, Av. Prof. Dr. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo, SP, 05508-270, Brazil.
Horwald Alexander Bedoya LlanoDepartamento de Medicina Veterinária Preventiva e Saúde Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, Av. Prof. Dr. Orlando Marques de Paiva, 87, Cidade Universitária, São Paulo, SP, 05508-270, Brazil.
Saulo Petinatti PavariniSetor de Patologia Veterinária, Departamento de Patologia Clínica, Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul, Av. Bento Gonçalves, 9090, Bairro Agronomia, Porto Alegre, RS, 91540-000, Brazil.
Universidade Federal do Rio Grande do Sul · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcocystis neurona is the main agent associated with equine protozoal myeloencephalitis (EPM). Apart from horses, S. neurona has been occasionally described causing neurologic disease in several other terrestrial animals as well as mortality in marine mammals. Herein, we describe the clinical, pathological, and molecular findings of a fatal case of S. neurona-associated meningoencephalitis in a domestic cat. The causing agent was analyzed by multilocus genotyping, confirming the presence of S. neurona DNA in the tissue samples of the affected animal. Significant molecular differences were found in relation to S. neurona isolates detected in other regions of the Americas. In addition, the parasite was identical to Sarcocystis sp. identified in opossum sporocysts in Brazil at molecular level, which suggests that transmission of. S. neurona in Brazil might involve variants of the parasite different from those found elsewhere in the Americas. Studies including more samples of S. neurona would be required to test this hypothesis, as well as to assess the impact of this diversity.

Indexed as

AnimalsBrazilCat DiseasesCatsCentral Nervous System Protozoal InfectionsDNA, ProtozoanEncephalomyelitisHorse DiseasesHorsesMeningoencephalitisOpossumsSarcocystisSarcocystosisDNA, ProtozoanFelineGenotypingPolymerase chain reactionProtozoal meningoencephalitis

Identifiers

PMID31901995
PMCPMC7088143
OpenAlexW2997384101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.