Evidence map›Paper›PMID 31901872›Full record

ArticleEBioMedicine2020

The CD24

Zhenhua Zhou, Yan Li, Muyu Kuang, Xudong Wang, Qi Jia, Jiashi Cao, Jingjing Hu, Sujia Wu, Zhiwei Wang, Jianru Xiao

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in EBioMedicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.8field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 35 citations in OpenAlex.

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  13. Emerging phagocytosis checkpoints in cancer immunotherapy.Signal transduction and targeted therapy · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Zhenhua ZhouDepartment of Orthopaedic Oncology, Changzheng Hospital, Naval Medical University (The Second Military Medical University), Shanghai, 200003,China.
Yan LiCancer Institute, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, 200032,China.
Muyu KuangHuadong Hospital, Fudan University, Shanghai,200040, China.
Xudong WangDepartment of Orthopaedic Oncology, Changzheng Hospital, Naval Medical University (The Second Military Medical University), Shanghai, 200003,China.
Qi JiaDepartment of Orthopaedic Oncology, Changzheng Hospital, Naval Medical University (The Second Military Medical University), Shanghai, 200003,China.
Jiashi CaoDepartment of Orthopaedic Oncology, Changzheng Hospital, Naval Medical University (The Second Military Medical University), Shanghai, 200003,China.
Jingjing HuClinical Research Center, Changhai Hospital, Naval Medical University (The Second Military Medical University), Shanghai 200433, China.
Sujia WuDepartment of Orthopedics, Nanjing General Hospital of Nanjing Military Region, Nanjing, Jiangsu, 210002, China.
Zhiwei WangDepartment of Orthopedics, Changhai Hospital, Naval Medical University (The Second Military Medical University), Shanghai, 200433, China. Electronic address: shwangzhiwei@vip.sina.com.
Jianru XiaoDepartment of Orthopaedic Oncology, Changzheng Hospital, Naval Medical University (The Second Military Medical University), Shanghai, 200003,China. Electronic address: jianruxiao63@126.com.
Second Military Medical University · CNChanghai Hospital · CNFudan University Shanghai Cancer Center · CNHuadong Hospital · CNNanjing General Hospital of Nanjing Military Command · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOsteosarcoma is the most common primary aggressive bone tumor affecting children and young adolescents. Metastases are often resistant to conventional chemotherapy and mean short-term survival. Development of valuable diagnostic indicators and targeting agents will have important implications for clinical diagnosis by the identification and characterization of molecules that contribute to its aggressive behavior.

methodsWe examined differential expression levels of common stem cell markers in osteosarcoma parental and sphere cells. In addition, we further analyzed the changes of candidate common stem cell markers before and after in vitro chemotherapy of osteosarcoma cells. The biological functions of CD24

findingsCD24

interpretationCD24

fundingNational Natural Science Foundation of China (No.81772857); Shanghai Science and Technology Commission (18140902000); Shanghai Municipal Health Commission (2017ZZ01017; 17411950301).

Indexed as

AnimalsApoptosisBiomarkers, TumorCarcinogenesisCD24 AntigenCell Line, TumorDrug Resistance, NeoplasmHumansMice, Inbred BALB CMice, NudeNeoplasm InvasivenessNeoplasm MetastasisNeoplasm ProteinsNeoplastic Stem CellsOsteosarcomaSpheroids, CellularBiomarkers, TumorCD24 AntigenNeoplasm Proteins

Identifiers

PMID31901872
PMCPMC6948162
OpenAlexW2998651806

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.