SynthesisWorld journal of surgery2020
The Efficacy of Prophylactic Negative Pressure Wound Therapy for Closed Incisions in Breast Surgery: A Systematic Review and Meta-Analysis.
Synthesis in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prevention of Postoperative Complications by Negative Pressure Therapy After Complex Breast Cancer Surgery: a Prospective Randomized Controlled Trial
Is Negative Pressure Wound Therapy Associated With a Decreased Risk of Postoperative Seroma in Breast Cancer Patients Who Have Undergone Mastectomy?
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 48 citations in OpenAlex.
- Clinical and economic impact of incisional negative pressure wound therapy in breast surgery: meta-analysis.The British journal of surgery · 2026Pooled it
- Efficacy of prophylactic negative pressure wound therapy after open ventral hernia repair: a systematic review meta-analysis.BMC surgery · 2023Pooled it
- The wound adjuncts effect of closed incision negative pressure wound therapy on stopping groin surgical site wound infection in arterial surgery: A meta-analysis.International wound journal · 2023Pooled it
- Comparison of surgical site infection (SSI) between negative pressure wound therapy (NPWT) assisted delayed primary closure and conventional delayed primary closure in grossly contaminated emergency abdominal surgeries: a randomized controlled trial.Langenbeck's archives of surgery · 2023Trial
- Within-patient randomized clinical trial comparing incisional negative-pressure wound therapy with suction drains in gender-affirming mastectomies.The British journal of surgery · 2021Trial
- Can the Use of Closed Incision Negative Pressure Wound Therapy in Immediate Prepectoral Breast Reconstruction With Polyurethane-Coated Implants Reduce the Rate of Early Complications?: A Comparative Study.Aesthetic surgery journal · 2026Article
- Postoperative Impact of Closed Incision Negative Pressure Therapy Following Oncoplastic Breast Surgery.Annals of surgical oncology · 2026Article
- Article
- Wound Dressing and Postoperative Complications Following Breast Reduction: A Retrospective Study of 250 Patients.Aesthetic surgery journal. Open forum · 2026Article
- Managing Drainless Mastectomy With Closed Incision Negative Pressure Wound Therapy Using Full-coverage Foam Dressings.Plastic and reconstructive surgery. Global open · 2025Article
- Closed-Incision Negative Pressure Therapy: Scoping Review and Multidisciplinary Consensus Recommendations of the Spanish Observatory of Infection in Surgery.International wound journal · 2025Article
- Improving the Patient Experience in Breast Reconstruction: ERAS and Beyond.Journal of clinical medicine · 2025Review
- Preclinical Evaluation of Closed Incisional Negative Pressure Therapy on Post-Surgical Oedema and Lymphatic Activity.International wound journal · 2025Article
- Salvage of Nipple-areolar Complex Venous Congestion Following Reduction Mammaplasty with Full-coverage Incisional Negative Pressure Wound Therapy.Journal of plastic and reconstructive surgery · 2025Article
- No closure of the linea alba cervicalis reduces complications in endoscopic thyroidectomy.Scientific reports · 2025Article
- Mechanically Powered Negative Pressure Dressing Enhances Surgical Incision Cosmesis: A Randomized Trial.Plastic and reconstructive surgery. Global open · 2025Article
- Mechanically powered negative pressure dressing reduces surgical site infection after stoma reversal.Surgery open science · 2025Article
- A Cost-Utility Analysis of the Use of -125 mm Hg Closed-incision Negative Pressure Therapy in Oncoplastic Breast Surgery.Plastic and reconstructive surgery. Global open · 2024Article
- Efficacy of Closed-Incision Negative Pressure Wound Therapy in Reducing Postoperative Complications in Breast Reconstruction After Radiotherapy: A Propensity Score Analysis.Aesthetic surgery journal. Open forum · 2024Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNegative pressure wound therapy (NPWT) is a promising advance in the management of closed surgical incisions. NPWT application induces several effects locally within the wound including reduced lateral tension and improving lymphatic drainage. As a result, NPWT may improve wound healing and reduce surgical site complications. We aim to evaluate the efficacy of prophylactic application of NPWT in preventing surgical site complications for closed incisions in breast surgery.
methodsThis systematic review was reported according to PRISMA guidelines. The protocol was published in PROSPERO (CRD42018114625). Medline, Embase, CINAHL and Cochrane Library databases were searched for studies which compare the efficacy of NPWT versus non-NPWT dressings for closed incisions in breast surgery. Specific outcomes of interest were total wound complications, surgical site infection (SSI), seroma, haematoma, wound dehiscence and necrosis.
resultsSeven studies (1500 breast incisions in 904 patients) met the inclusion criteria. NPWT was associated with a significantly lower rate of total wound complications [odds ratio (OR) 0.36; 95% CI 0.19-069; P = 0.002], SSI (OR 0.45; 95% CI 0.24-0.86; P = 0.015), seroma (OR 0.28; 95% CI 0.13-0.59; P = 0.001), wound dehiscence (OR 0.49; 95% CI 0.32-0.72; P < 0.001) and wound necrosis (OR 0.38; 95% CI 0.19-0.78; P = 0.008). There was no significant difference in haematoma rate (OR 0.8; 95% CI 0.19-3.2; P = 0.75). Statistically significant heterogeneity existed for total wound complications, but no other outcomes.
conclusionCompared with conventional non-NPWT dressings, prophylactic application of NPWT is associated with significantly fewer surgical site complications including SSI, seroma, wound dehiscence and wound necrosis for closed breast incisions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.