ReviewAnalytical and bioanalytical chemistry2020
Potential of Raman spectroscopy for the analysis of plasma/serum in the liquid state: recent advances.
Review in Analytical and bioanalytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Raman Spectroscopy as a Potential Adjunct of Thyroid Nodule Evaluation: A Systematic Review.International journal of molecular sciences · 2023Pooled it
- Spectroscopic technologies and data fusion: Applications for the dairy industry.Frontiers in nutrition · 2022Pooled it
- Gold- or Silver-Nanoparticle SERS Platforms for Plasma-Based Diagnostics and AI-Driven Analysis.Sensors (Basel, Switzerland) · 2026Review
- Raman Spectral Signatures of Human Neutrophils: A Single-Cell Approach.Journal of biophotonics · 2026Article
- Raman spectroscopy supported by machine learning reveals changes in balance of macromolecules in diabetic rat serum.Analytical and bioanalytical chemistry · 2025Article
- A novel approach to smart-assisted schizophrenia screening based on Raman spectroscopy and deep learning.Scientific reports · 2025Article
- Article
- Rapid Microfluidic Ion-Exchange Optode System for Point-of-Care Determination of Sodium Concentration in Serum.Biosensors · 2025Article
- Evaluation of Peri-Implantitis through Fourier-Transform Infrared Spectroscopy on Saliva.Journal of proteome research · 2025Article
- Raman spectroscopy on dried blood plasma allows diagnosis and monitoring of colorectal cancer.MedComm · 2024Article
- Insights into the molecular basis of gastric mucosa as a first step for using Raman microscopy in paediatrics.Heliyon · 2024Article
- Rapid detection of lung cancer based on serum Raman spectroscopy and a support vector machine: a case-control study.BMC cancer · 2024Article
- Rapid diagnosis of celiac disease based on plasma Raman spectroscopy combined with deep learning.Scientific reports · 2024Article
- Current Trends of Raman Spectroscopy in Clinic Settings: Opportunities and Challenges.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Review
- Raman Spectroscopy and Cystic Fibrosis Disease: An Alternative Potential Tool for Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulator Response Differentiation-A Pilot Study Based on Serum Samples.Molecules (Basel, Switzerland) · 2024Article
- Surface-Enhanced Raman Analysis of Uric Acid and Hypoxanthine Analysis in Fractionated Bodily Fluids.Nanomaterials (Basel, Switzerland) · 2023Article
- Raman Spectroscopy of Carotenoid Compounds for Clinical Applications-A Review.Molecules (Basel, Switzerland) · 2022Review
- Quantitative Raman Analysis of Carotenoid Protein Complexes in Aqueous Solution.Molecules (Basel, Switzerland) · 2022Article
- The Mechanism of Dynamic Interaction between Doxorubicin and Calf Thymus DNA at the Single-Molecule Level Based on Confocal Raman Spectroscopy.Micromachines · 2022Article
- Comparative Study of Sample Carriers for the Identification of Volatile Compounds in Biological Fluids Using Raman Spectroscopy.Molecules (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is compelling evidence in the literature to support the application of Raman spectroscopy for analysis of bodily fluids in their native liquid state. Naturally, the strategies described in the literature for Raman spectroscopic analysis of liquid samples have advantages and disadvantages. Herein, recent advances in the analysis of plasma/serum in the liquid state are reviewed. The potential advantages of Raman analysis in the liquid form over the commonly employed infrared absorption analysis in the dried droplet form are initially highlighted. Improvements in measurement protocols based on inverted microscopic geometries, clinically adaptable substrates, data preprocessing and analysis and applications for routine monitoring of patient health as well as therapeutic administration are reviewed. These advances suggest that clinical translation of Raman spectroscopy for rapid biochemical analysis can be a reality. In the future, this method will prove to be highly beneficial to clinicians for rapid screening and monitoring of analytes and drugs in the biological fluids, and to the patients themselves, enabling early treatment, before the disease becomes symptomatic, allowing early recovery.
Indexed as
Identifiers
31900532What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.