ArticleSkeletal radiology2020
Value of multidetector computed tomography for the differentiation of delayed aseptic and septic complications after total hip arthroplasty.
Article in Skeletal radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- Periprosthetic joint infection and heterotopic ossification after total hip arthroplasty: systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- Diagnostic and prognostic relevance of plain radiographs for periprosthetic joint infections of the hip: a literature review.European journal of medical research · 2024Pooled it
- Periosteal reaction of the femur following total hip arthroplasty can be a sign of periprosthetic joint infection (PJI). A case report of Staphylococcal PJI and management.Radiology case reports · 2026Article
- The accuracy of spectral CT with quantitative parameters in differentiating septic from aseptic periprosthetic complications.Insights into imaging · 2026Article
- Evaluating Hip Periprosthetic Joint Infection with Metal-artifact-reduction MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2025Article
- Editorial on the validity of plain radiographs in low-grade periprosthetic hip infections.Annals of medicine · 2024Article
- Increased cortical density in popliteal lymphadenopathy as a promising radiological sign to help differentiate adverse local tissue reaction from infections in complications following a knee arthroplasty-three case reports.Quantitative imaging in medicine and surgery · 2024Article
- Bone and Joint Infections: The Role of Imaging in Tailoring Diagnosis to Improve Patients' Care.Journal of personalized medicine · 2021Review
- Percutaneous cementoplasty of periprosthetic loosening: can interventional radiologists offer an alternative to revision surgery?European radiology · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe differentiation between delayed aseptic and septic complications of total hip arthroplasty is crucial to allow appropriate surgical planning and timely antimicrobial treatment. The aim of this study was to investigate the utility of multidetector computed tomography (CT) findings to diagnose aseptic mechanical loosening, granulomatous reaction, and periprosthetic joint infection in patients who underwent total hip arthroplasty before revision surgery. MATERIALS AND
methodsNinety-six consecutive patients with a clinical suspicion of periprosthetic complications underwent revision surgery over an 8-year period. All patients had been evaluated preoperatively using multidetector CT without contrast media. Two blinded musculoskeletal radiologists reviewed multidetector CT images, including periprosthetic soft-tissue accumulation, prosthetic acetabular malposition, periprosthetic osteolysis, enlarged iliac lymph nodes, and heterotopic ossification. Risk factors for aseptic and septic loosening were identified using multivariate analysis.
resultsMultidetector CT-related variables independently associated with periprosthetic joint infection were high periprosthetic soft-tissue accumulation, periprosthetic osteolysis without expansile periosteal reaction and enlarged iliac lymph nodes. On the other hand, the absence of the following radiological signs: low or high periprosthetic soft-tissue accumulation, mild or severe periprosthetic osteolysis, and enlarged iliac lymph nodes, were predictors of aseptic mechanical loosening. Low periprosthetic soft-tissue accumulation, severe periprosthetic osteolysis with expansile periosteal reaction, and mild acetabular malposition were significant variables associated with granulomatosis.
conclusionMultidetector CT findings are useful to differentiate between aseptic and septic complications before revision surgery. The presence of osteolysis with expansile periosteal reaction appeared to be a time-dependent variable.
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