Evidence map›Paper›PMID 31900387›Full record

ArticleNature communications2020

Mapping axon initial segment structure and function by multiplexed proximity biotinylation.

Hamdan Hamdan, Brian C Lim, Tomohiro Torii, Abhijeet Joshi, Matthias Konning, Cameron Smith, Donna J Palmer, Philip Ng, Christophe Leterrier, Juan A Oses-Prieto and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed
8.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 104 citations in OpenAlex.

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  20. TRIM46 Is Required for Microtubule Fasciculation In Vivo But Not Axon Specification or Axon Initial Segment Formation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article

10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Hamdan HamdanDepartment of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Brian C LimDepartment of Neuroscience, Baylor College of Medicine, Houston, TX, USA.ORCID http://orcid.org/0000-0001-5339-8487
Tomohiro ToriiDepartment of Neuroscience, Baylor College of Medicine, Houston, TX, USA.ORCID http://orcid.org/0000-0002-0039-923X
Abhijeet JoshiDepartment of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Matthias KonningDepartment of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Cameron SmithDepartment of Neuroscience, Baylor College of Medicine, Houston, TX, USA.ORCID http://orcid.org/0000-0002-2079-4667
Donna J PalmerDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Philip NgDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.
Christophe LeterrierAix-Marseille Univ, CNRS, INP, NeuroCyto, Marseille, France.ORCID http://orcid.org/0000-0002-2957-2032
Juan A Oses-PrietoDepartment of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.ORCID http://orcid.org/0000-0003-4759-2341
Alma L BurlingameDepartment of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.
Matthew N RasbandDepartment of Neuroscience, Baylor College of Medicine, Houston, TX, USA. rasband@bcm.edu.ORCID http://orcid.org/0000-0001-8184-2477
Baylor College of Medicine · USUniversity of California, San Francisco · USAlfaisal University · SACentre National de la Recherche Scientifique · FR

Funding

Bio-Organic Biomedical Mass Spectromy ResourceP41GM103481 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BURLINGAME, ALMA L · 2012 to 2015
$6.4M
Neuroglial Interactions at the Node of RanvierR01NS044916 · NINDS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI RASBAND, MATTHEW N · 2002 to 2020
$4.2M
Mechanisms of CNS node of Ranvier formation.R01NS069688 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI RASBAND, MATTHEW N · 2010 to 2019
$3.4M
Neuroglial interactions at the node of RanvierR37NS044916 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI RASBAND, MATTHEW N · 2012 to 2018
$2.9M
NIGMS NIH HHS P41 GM103481NINDS NIH HHS R01 NS044916NINDS NIH HHS R01 NS069688NINDS NIH HHS R37 NS044916
6 · The paper itself

Abstract

Axon initial segments (AISs) generate action potentials and regulate the polarized distribution of proteins, lipids, and organelles in neurons. While the mechanisms of AIS Na

Indexed as

AnimalsAxon Initial SegmentAxonsBiotinylationHumansMass SpectrometryMiceNeuronsProtein TransportProteomeRatsRats, Sprague-DawleyProteome

Identifiers

PMID31900387
PMCPMC6941957
OpenAlexW2996955222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.