Evidence map›Paper›PMID 31900343›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

Polysaccharide Capsules Equip the Human Symbiont

Samantha Hsieh, Nathan T Porter, David L Donermeyer, Stephen Horvath, Gregory Strout, Brian T Saunders, Nan Zhang, Bernd Zinselmeyer, Eric C Martens, Thaddeus S Stappenbeck and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
0.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Samantha HsiehDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0002-1846-2583
Nathan T PorterDivision of Industrial Biotechnology, Chalmers University of Technology, Gothenburg, SE-412 96 Sweden.ORCID 0000-0001-8523-6909
David L DonermeyerDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.
Stephen HorvathDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0001-5324-1666
Gregory StroutWashington University Center for Cellular Imaging, Washington University School of Medicine, St. Louis, MO 63110; and.
Brian T SaundersDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0002-9111-5473
Nan ZhangDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.
Bernd ZinselmeyerDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0003-4172-6767
Eric C MartensDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109.
Thaddeus S StappenbeckDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.
Paul M AllenDepartment of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110.
Washington University in St. Louis · USChalmers University of Technology · SEUniversity of Michigan · US

Funding

Cellular Biotechnology Training Program (CBTP) - Years 31-35T32GM145304 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Guizhi Zhu · 2022 to 2026
$2.6M
Immune Regulation by Bacteroides Polysaccharide CapsulesR21AI142257 · NIAID · WASHINGTON UNIVERSITY · PI ALLEN, PAUL M, MARTENS, ERIC C · 2019 to 2020
$502k
Initiation of symbiont-driven inflammatory bowel diseases by genetic mutations in T cells and antigen-presenting cellsF30DK114950 · NIDDK · WASHINGTON UNIVERSITY · PI BAI, SAMANTHA HSIEH · 2017 to 2019
$111k
NIAID NIH HHS R21 AI142257NIDDK NIH HHS F30 DK114950NIGMS NIH HHS T32 GM145304
6 · The paper itself

Abstract

Bacteria express multiple diverse capsular polysaccharides (CPSs) for protection against environmental and host factors, including the host immune system. Using a mouse TCR transgenic CD4

Indexed as

AnimalsAntigens, BacterialBacterial CapsulesBacteroides thetaiotaomicronCD4-Positive T-LymphocytesGastrointestinal MicrobiomeHomeodomain ProteinsHost Microbial InteractionsHumansImmunity, MucosalIntestinal MucosaLymphocyte ActivationMiceMice, KnockoutPolysaccharides, BacterialSymbiosisAntigens, BacterialHomeodomain ProteinsPolysaccharides, BacterialRAG-1 protein

Identifiers

PMID31900343
PMCPMC7002182
OpenAlexW2997096496

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.