Evidence map›Paper›PMID 31900341›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2020

The Prostaglandin D

Oyebola O Oyesola, Carolina Duque, Linda C Huang, Elisabeth M Larson, Simon P Früh, Lauren M Webb, Seth A Peng, Elia D Tait Wojno

Open access · greenAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 47 citations in OpenAlex.

  1. Update on environmental determinants of allergic diseases.The Journal of allergy and clinical immunology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. PGI2 restricts trained ILC2 responses in allergic inflammation.Journal of immunology (Baltimore, Md. : 1950) · 2025
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Induction of Siglec-FFrontiers in immunology · 2023
    Article
  16. Review
  17. Heterogeneity of type 2 innate lymphoid cells.Nature reviews. Immunology · 2022
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Oyebola O OyesolaBaker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, NY 14850.ORCID 0000-0002-5347-7502
Carolina DuqueBaker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, NY 14850.ORCID 0000-0003-3737-3858
Linda C HuangBaker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, NY 14850.ORCID 0000-0002-7582-3090
Elisabeth M LarsonBaker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, NY 14850.ORCID 0000-0001-9195-5061
Simon P FrühBaker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, NY 14850.ORCID 0000-0002-4757-8315
Lauren M WebbBaker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, NY 14850.
Seth A PengBaker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, NY 14850.
Elia D Tait WojnoBaker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, NY 14850; etwojno@uw.edu.ORCID 0000-0003-2822-296X
Cornell University · USUniversity of Washington · US

Funding

Role of the prostaglandin D2 receptor CRTH2 in helminth-induced type 2 inflammation in the intestine.R01AI130379 · NIAID · UNIVERSITY OF WASHINGTON · PI Elia D Tait Wojno · 2017 to 2026
$3.5M
Prostaglandin regulation of type 2 inflammationK22AI116729 · NIAID · CORNELL UNIVERSITY · PI TAIT WOJNO, ELIA D · 2016 to 2017
$267k
NIAID NIH HHS K22 AI116729NIAID NIH HHS R01 AI130379
6 · The paper itself

Abstract

Group 2 innate lymphoid cells (ILC2s) are rare innate immune cells that accumulate in tissues during allergy and helminth infection, performing critical effector functions that drive type 2 inflammation. ILC2s express ST2, the receptor for the cytokine IL-33, and chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2), a receptor for the bioactive lipid prostaglandin D

Indexed as

Adoptive TransferAnimalsCell MovementCell ProliferationCells, CulturedDisease Models, AnimalFemaleHumansHypersensitivityImmunity, InnateInterleukin-33LungLymphocytesMiceMice, KnockoutNippostrongylusIl33 protein, mouseInterleukin-33Prostaglandin D2prostaglandin D2 receptorReceptors, ImmunologicReceptors, ProstaglandinRecombinant Proteins

Identifiers

PMID31900341
PMCPMC6994842
OpenAlexW2998233305

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.