ArticleBMJ case reports2020
Adie's tonic pupil presenting with unilateral photophobia successfully treated with dilute pilocarpine.
Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 11 citations in OpenAlex.
- Persistent Pupillary Dilation and Irreversible Mydriasis in HLA-B27-Associated Uveitis.Cureus · 2025Article
- Adie's pupil and systemic manifestations: a rare unilateral presentation.GMS ophthalmology cases · 2024Article
- How Does SARS-CoV-2 Affect Our Eyes-What Have We Learnt So Far about the Ophthalmic Manifestations of COVID-19?Journal of clinical medicine · 2022Review
- Adie's Pupil: A Diagnostic Challenge for the Physician.Medical science monitor : international medical journal of experimental and clinical research · 2022Review
- Pupillary light response after cataract surgery in healthy patients.Japanese journal of ophthalmology · 2021Observational
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A 40-year-old healthy man presented with a 4-month history of photophobia, blurred vision and a right dilated pupil. Examination revealed a right pupil that was not reactive to light but constricted strongly to a near target and slowly redilated when he looked back in the distance. Pharmacological testing with dilute pilocarpine 0.1% resulted in constriction of the right pupil but no change in the left pupil. This also resulted in resolution of his photophobia and blurry vision. Neurological examination was otherwise normal, and a diagnosis of Adie's tonic pupil was made. The main differential diagnosis to consider for a large pupil is a third nerve palsy, pharmacological mydriasis, tonic pupil and local iris processes, such as iris sphincter tears from trauma. Knowledge of the key features of these conditions can avoid wasted resources from unnecessary testing. Dilute pilocarpine 0.1% three times a day can be considered as a pharmacological therapy for symptomatic relief.
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