Evidence map›Paper›PMID 31899983›Full record

ReviewExpert opinion on drug discovery2020

Organoid and pluripotent stem cells in Parkinson's disease modeling: an expert view on their value to drug discovery.

Nick Marotta, Soojin Kim, Dimitri Krainc

Open access · greenAbstract readReview
In one paragraph

Review in Expert opinion on drug discovery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Precision Medicine on the Fly: Using Drosophila to Decipher Gene-Environment Interactions in Parkinson's Disease.Toxicological sciences : an official journal of the Society of Toxicology · 2021
    Article
  13. Review
  14. Review
  15. Review
  16. Parkinson's disease treatment: past, present, and future.Journal of neural transmission (Vienna, Austria : 1996) · 2020
    Review
  17. Frontiers in cell and developmental biology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nick MarottaDepartment of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Soojin KimDepartment of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Dimitri KraincDepartment of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Northwestern University · US

Funding

The Role of Lysosomal Glucocerebrosidase in SynucleinopathiesR01NS076054 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KRAINC, DIMITRI · 2011 to 2020
$4.1M
Rational derivation of DA neuron subtypes from iPS cells for improved modelling of Parkinson's diseaseR01NS096240 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI AWATRAMANI, RAJESHWAR B, KRAINC, DIMITRI · 2016 to 2020
$3.0M
NINDS NIH HHS R01 NS076054NINDS NIH HHS R01 NS096240
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Models, BiologicalAnimalsAntiparkinson AgentsBrainDopaminergic NeuronsDrug DiscoveryHumansInduced Pluripotent Stem CellsOrganoidsParkinson DiseaseAntiparkinson Agentsdopaminergic neuronsGBAInduced pluripotent stem cellsmidbrainneurodegenerationorganoidParkinson’s diseasetherapeuticsα-synuclein

Identifiers

PMID31899983
PMCPMC7065944
OpenAlexW2997423123

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.