ArticlePloS one2020
Disparate effects of antibiotic-induced microbiome change and enhanced fitness in Daphnia magna.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 52 citations in OpenAlex.
- Investigating the core microbiome concept: Daphnia as a case study.Environmental microbiome · 2025Article
- Natural and lab-derived microbiomes differentially shape stressor interaction patterns of Daphnia magna.The ISME journal · 2025Article
- Microbial diversity and community structure of microalgae (Nannochloropsis oculata) and rotifer (Brachionus plicatilis) in aquaculture by 16S rRNA amplicon-based sequencing.Antonie van Leeuwenhoek · 2024Article
- Manipulating a host-native microbial strain compensates for low microbial diversity by increasing weight gain in a wild bird population.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Prediction of New-Onset Diabetes Mellitus within 12 Months after Liver Transplantation-A Machine Learning Approach.Journal of clinical medicine · 2023Article
- Prolonged survival time of Daphnia magna exposed to polylactic acid breakdown nanoplastics.PloS one · 2023Article
- Stochastic variation in gut bacterial community affects reproductive rates in the water flea Daphnia magna.FEMS microbiology ecology · 2022Article
- Targeted Manipulation of Abundant and Rare Taxa in themSystems · 2021Article
- Understanding Biofilm Formation in Ecotoxicological Assays With Natural and Anthropogenic Particulates.Frontiers in microbiology · 2021Article
- Characterization of key bacterial species in the Daphnia magna microbiota using shotgun metagenomics.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is a common view that an organism's microbiota has a profound influence on host fitness; however, supporting evidence is lacking in many organisms. We manipulated the gut microbiome of Daphnia magna by chronic exposure to different concentrations of the antibiotic Ciprofloxacin (0.01-1 mg L-1), and evaluated whether this affected the animals fitness and antioxidant capacity. In line with our expectations, antibiotic exposure altered the microbiome in a concentration-dependent manner. However, contrary to these expectations, the reduced diversity of gut bacteria was not associated with any fitness detriment. Moreover, the growth-related parameters correlated negatively with microbial diversity; and, in the daphnids exposed to the lowest Ciprofloxacin concentrations, the antioxidant capacity, growth, and fecundity were even higher than in control animals. These findings suggest that Ciprofloxacin exerts direct stimulatory effects on growth and reproduction in the host, while microbiome- mediated effects are of lesser importance. Thus, although microbiome profiling of Daphnia may be a sensitive tool to identify early effects of antibiotic exposure, disentangling direct and microbiome-mediated effects on the host fitness is not straightforward.
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