Evidence map›Paper›PMID 31899499›Full record

Trial reportPhysical therapy2020

The Effects of Home Exercise in Older Women With Vertebral Fractures: A Pilot Randomized Controlled Trial.

Jenna C Gibbs, Caitlin McArthur, John D Wark, Lehana Thabane, Samuel C Scherer, Sadhana Prasad, Alexandra Papaioannou, Nicole Mittmann, Judi Laprade, Sandra Kim and 8 more

Open access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Physical therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Effect of a home-based resistance exercise program in elderly participants with osteoporosis: a randomized controlled trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2022
    Trial
  5. Trial
  6. Effectiveness and safety of physical exercise and health education for the management of osteoporotic vertebral fractures: a systematic review and meta-analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Review
  7. Review
  8. Article
  9. The role of physical performance measures in the physiotherapy assessment and management of older adults with osteoporotic vertebral fractures: a narrative review.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Review
  10. Regular physical activity improves physical function and health-related quality of life among middle-aged and older women who suffered a fragility fracture-a population-based cohort.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Article
  11. Article
  12. International consensus on the non-pharmacological and non-surgical management of osteoporotic vertebral fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2023
    Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 12 institutions in 2 countries.

Jenna C GibbsDepartment of Kinesiology and Physical Education, McGill University, Montreal, Quebec, Canada.
Caitlin McArthurDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada; and GERAS Centre for Aging Research, Hamilton Health Sciences, Hamilton, Ontario, Canada.
John D WarkDepartment of Medicine, University of Melbourne, Parkville, Victoria, Australia; and Bone and Mineral Medicine, Royal Melbourne Hospital, Parkville, Victoria, Australia.
Lehana ThabaneDepartment of Health Research Methods, Evidence, and Impact, McMaster University.
Samuel C SchererDepartment of Medicine, University of Melbourne; Royal Melbourne Hospital; and Broadmeadows Health Services, Northern Health, Melbourne, Australia.
Sadhana PrasadDepartment of Medicine, McMaster University.
Alexandra PapaioannouDepartment of Medicine, McMaster University; GERAS Centre for Aging Research, Hamilton Health Sciences; and Department of Health Research Methods, Evidence, and Impact, McMaster University.
Nicole MittmannSunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Judi LapradeDepartment of Surgery, University of Toronto, Toronto, Ontario, Canada; and Ontario Osteoporosis Strategy, Osteoporosis Canada, Toronto, Ontario, Canada.
Sandra KimDepartment of Medicine, University of Toronto; and Centre for Osteoporosis and Bone Health, Women's College Hospital, Toronto, Ontario, Canada.
Aliya KhanDepartment of Medicine, McMaster University.
David L KendlerDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Keith D HillGrad Dip Physio, BAppSc (Physio), School of Primary and Allied Health Care, Peninsula Campus, Monash University, Frankston, Australia.
Angela M CheungDepartment of Medicine, University of Toronto; and Osteoporosis Program and Centre of Excellence in Skeletal Health Assessment, University Health Network and Sinai Health System, Toronto, Ontario, Canada.
Robert BleakneyDepartment of Medical Imaging, University of Toronto; and Centre of Excellence in Skeletal Health Assessment, University Health Network and Sinai Health System.
Maureen C AsheDepartment of Family Practice, University of British Columbia; and Centre for Hip Health and Mobility, Vancouver, British Columbia, Canada.
Jonathan D AdachiDepartment of Medicine, McMaster University.
Lora M GiangregorioDepartment of Kinesiology, University of Waterloo; and Schlegel-University of Waterloo Research Institute for Aging, Waterloo, Ontario, Canada; and KITE, Toronto Rehab-University Health Network, Toronto, Ontario, Canada.
McMaster University · CAHamilton Health Sciences · CAThe University of Melbourne · AUUniversity Health Network · CABritish Columbia Centre of Excellence for Women's Health · CAMcGill University · CAMonash University · AUOsteoporosis Canada · CASunnybrook Health Science Centre · CAUniversity of British Columbia · CAUniversity of Toronto · CAWomen's College Hospital · CA

Funding

CIHR MOP 123445
6 · The paper itself

Abstract

backgroundRegular exercise is advocated in osteoporosis guidelines to prevent fractures. Few studies have evaluated the effect of exercise on functional performance, posture, and other outcomes that are important to patients after vertebral fractures.

objectiveThis pilot study will explore the effect of home exercise versus control on functional performance, posture, and patient-reported outcome measures.

designThis study was a parallel 2-arm pilot feasibility trial with 1:1 randomization to exercise or attentional control groups.

settingThis study took place in 5 Canadian and 2 Australian academic or community hospitals/centers.

participantsThis study included 141 women ≥65 years of age with radiographically confirmed vertebral fractures.

interventionA physical therapist delivered exercise and behavioral counseling in 6 home visits over 8 months and monthly calls. Participants were to exercise ≥3 times weekly. Controls received equal attention. MEASUREMENTS: Functional performance, posture, quality of life, pain, and behavior-change outcomes were assessed at baseline and after 6 (questionnaires only) and 12 months. Adherence to exercise was assessed by calendar diary. All t tests examined between-group mean differences (MD) in change from baseline in intention-to-treat and per-protocol analyses.

resultsThere was a small effect of exercise on 5 times sit-to-stand test versus control (MD = -1.58 [95% CI = -3.09 to -0.07], intention-to-treat; MD = -1.49 [95% CI = -3.12 to 0.16], per-protocol). There were no other major or statistically significant MDs for any other measured outcomes after follow-up. Adherence declined over time. LIMITATIONS: Treatment effects on variables may have been underestimated due to multiple comparisons and underpowered analyses.

conclusionsOur exploratory estimate of the effect of exercise on functional leg muscle strength was consistent in direction and magnitude with other trials in individuals with vertebral fractures. Declining adherence to home exercise suggests that strategies to enhance long-term adherence might be important in future confirmatory trials.

Indexed as

Patient Reported Outcome MeasuresPhysical Functional PerformancePostureAgedExercise TherapyFeasibility StudiesFemaleFractures, SpontaneousHumansIntention to Treat AnalysisLegMuscle StrengthOsteoporosisPain MeasurementPatient CompliancePatient SelectionExerciseMobilityOsteoporosisQuality of LifeRehabilitationSpinal Fractures

Identifiers

PMID31899499
PMCPMC7439228
OpenAlexW2996971590

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.