Evidence map›Paper›PMID 31898795›Full record

ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2020

Leptospirosis: a neglected tropical zoonotic infection of public health importance-an updated review.

Krishnan Baby Karpagam, Balasubramanian Ganesh

Abstract readReview
PubMed Publisher
In one paragraph

Review in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
136citing papers in PubMed, 3 pooled it
23.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

136 citing papers in PubMed, 3 syntheses or guidelines pooled it, 267 citations in OpenAlex.

  1. Pooled it
  2. Antibiotics for treatment of leptospirosis.The Cochrane database of systematic reviews · 2024
    Pooled it
  3. Antibiotic prophylaxis for leptospirosis.The Cochrane database of systematic reviews · 2024
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Genetic Diversity ofPathogens (Basel, Switzerland) · 2026
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Advances in ELISA-based detection of equine leptospirosis.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  14. Article
  15. Article
  16. Transboundary and emerging diseases · 2026
    Article
  17. Article
  18. Molecular identification and phylogenetic characterization ofJournal of advanced veterinary and animal research · 2026
    Article
  19. Article
  20. Journal of tropical medicine · 2026
    Article

76 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Krishnan Baby KarpagamLaboratory Division, ICMR-National Institute of Epidemiology, R-127, 2nd Main Road, TNHB, Ayapakkam, Chennai, Tamil Nadu, 600 077, India.
Balasubramanian GaneshLaboratory Division, ICMR-National Institute of Epidemiology, R-127, 2nd Main Road, TNHB, Ayapakkam, Chennai, Tamil Nadu, 600 077, India. niedrbganesh@gmail.com.ORCID http://orcid.org/0000-0002-1978-2650
University of Madras · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leptospirosis is a zoonotic and waterborne disease worldwide. It is a neglected, reemerging disease of global public health importance with respect to morbidity and mortality both in humans and animals. Due to negligence, rapid, unplanned urbanization, and poor sanitation, leptospirosis emerges as a leading cause of acute febrile illness in many of the developing countries. Every individual has a risk of getting infected as domestic and wild animals carry leptospires; the at-risk population varies from the healthcare professionals, animal caretakers, farmers and agricultural workers, fishermen, rodent catchers, water sports people, National Disaster Response Force (NDRF) personnel, people who volunteer rescue operations in flood-affected areas, sanitary workers, sewage workers, etc. The clinical manifestations of leptospirosis range from flu-like illness to acute kidney failure (AKF), pneumonia, jaundice, pulmonary hemorrhages, etc. But many rare and uncommon clinical manifestations are being reported worldwide. This review will cover all possible updates in leptospirosis from occurrence, transmission, rare clinical manifestations, diagnosis, treatment, and prophylactic measures that are currently available, their advantages and the future perspectives, elaborately. There are less or very few reviews on leptospirosis in recent years. Thus, this work will serve as background knowledge for the current understanding of leptospirosis for researchers. This will provide a detailed analysis of leptospirosis and also help in finding research gaps and areas to focus on regarding future research perspectives.

Indexed as

Public HealthTropical ClimateAnimalsFarmersHumansLeptospiraLeptospirosisNeglected DiseasesRodentiaWaterborne DiseasesZoonosesClinical manifestationLaboratory diagnosisLeptospirosisProphylaxisTherapyTreatmentWeil’s disease

Identifiers

PMID31898795
OpenAlexW2997628747

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.