ArticleWorld journal of surgical oncology2020
Development and validation of a nomogram for preoperative prediction of lymph node metastasis in early gastric cancer.
Article in World journal of surgical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Endoscopic resection or radical gastrectomy? Risk factors for lymph node metastasis in early gastric cancer: a systematic review and meta-analysis.World journal of surgical oncology · 2026Pooled it
- Risk prediction models for lymph node metastasis in early gastric cancer patients: a systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- Machine learning for lymph node metastasis prediction of in patients with gastric cancer: A systematic review and meta-analysis.Frontiers in oncology · 2022Pooled it
- Development of a liver stiffness measurement-based nomogram model to identify early CKD risk in patients with MAFLD.BMC gastroenterology · 2026Article
- Oncologic outcomes of patients with negative nodal involvement on preoperative imaging undergoing surgery for gastric cancer.World journal of surgical oncology · 2025Article
- A nomogram for predicting non-curative resection in patients with early gastric cancer based on white light imaging.Scientific reports · 2025Article
- Combining biomarkers to construct a novel predictive model for predicting preoperative lymph node metastasis in early gastric cancer.Frontiers in oncology · 2025Article
- Nomogram for predicting cervical lymph node metastasis of papillary thyroid carcinoma using deep learning-based super-resolution ultrasound image.Discover oncology · 2024Article
- Unveiling the best predictive models for early‑onset metastatic cancer: Insights and innovations (Review).Oncology reports · 2024Review
- Integrating Machine Learning and the SHapley Additive exPlanations (SHAP) Framework to Predict Lymph Node Metastasis in Gastric Cancer Patients Based on Inflammation Indices and Peripheral Lymphocyte Subpopulations.Journal of inflammation research · 2024Article
- A Novel Method for Dynamically Assessing the Prognosis of Patients with pT1 Gastric Cancer: A Large Population-Based Dynamic Prognostic Analysis.Journal of oncology · 2023Article
- Analysis of risk factors for lymph node metastasis and prognosis study in patients with early gastric cancer: A SEER data-based study.Frontiers in oncology · 2023Article
- A nomogram based on platelet-to-lymphocyte ratio for predicting lymph node metastasis in patients with early gastric cancer.Frontiers in oncology · 2023Article
- Relationship between HER2 overexpression and long-term outcomes of early gastric cancer: a prospective observational study with a 6-year follow-up.BMC gastroenterology · 2022Observational
- Establishment of a nomogram for predicting lymph node metastasis in patients with early gastric cancer after endoscopic submucosal dissection.Frontiers in oncology · 2022Article
- Construction of a nomogram for preoperative prediction of the risk of lymph node metastasis in early gastric cancer.Frontiers in surgery · 2022Article
- Identification of novel antioxidant gene signature to predict the prognosis of patients with gastric cancer.World journal of surgical oncology · 2021Article
- A novel prognostic model based on epithelial-mesenchymal transition-related genes predicts patient survival in gastric cancer.World journal of surgical oncology · 2021Article
- Application of Machine Learning Algorithms to Predict Lymph Node Metastasis in Early Gastric Cancer.Frontiers in medicine · 2021Article
- A population-based study: how to identify high-risk T1 gastric cancer patients?American journal of cancer research · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe status of lymph nodes in early gastric cancer is critical to make further clinical treatment decision, but the prediction of lymph node metastasis remains difficult before operation. This study aimed to develop a nomogram that contained preoperative factors to predict lymph node metastasis in early gastric cancer patients.
methodsThis study analyzed the clinicopathologic features of 823 early gastric cancer patients who underwent gastrectomy retrospectively, among which 596 patients were recruited in the training cohort and 227 patients in the independent validation cohort. Significant risk factors in univariate analysis were further identified to be independent variables in multivariable logistic regression analysis, which were then incorporated in and presented with a nomogram. And internal and external validation curves were plotted to evaluate the discrimination of the nomogram.
resultsTotally, six independent predictors, including the tumor size, macroscopic features, histology differentiation, P53, carbohydrate antigen 19-9, and computed tomography-reported lymph node status, were enrolled in the nomogram. Both the internal validation in the training cohort and the external validation in the validation cohort showed the nomogram had good discriminations, with a C-index of 0.82 (95%CI, 0.78 to 0.86) and 0.77 (95%CI, 0.60 to 0.94) respectively.
conclusionsOur study developed a new nomogram which contained the most common and significant preoperative risk factors for lymph node metastasis in patients with early gastric cancer. The nomogram can identify early gastric cancer patients with the high probability of lymph node metastasis and help clinicians make more appropriate decisions in clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.