Evidence map›Paper›PMID 31898526›Full record

Trial reportBMC research notes2020

Associations between intestinal parasitic infections, anaemia, and diarrhoea among school aged children, and the impact of hand-washing and nail clipping.

Mahmud Abdulkader Mahmud, Mark Spigt, Afework Mulugeta Bezabih, Geert-Jan Dinant, Roman Blanco Velasco

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC research notes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01619254 (Hand Hygiene Promotion Activities), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01619254 nacompletednot on this map

Hand Hygiene Promotion Activities: Effect on Intestinal Parasitic Infections and Anaemia Among School-aged Children in Eastern Tigray, Ethiopia: a Factorial Randomised Controlled Trial

TypeinterventionalSponsorMekelle UniversityRan2012 to 2013Enrolled365ConditionsIntestinal Parasitic Infections, AnaemiaArmsHand washing with soap and hand finger nail clipping
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.

  1. Pooled it
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  13. Assessing Access to WASH in Urban Schools during COVID-19 in Kazakhstan: Case Study of Central Kazakhstan.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Mahmud Abdulkader MahmudMedical Microbiology and Immunology Department, Biomedical Division, School of Medicine, Mekelle University, PO. Box: 1871, Mekelle, Ethiopia. muheab2008@yahoo.com.ORCID http://orcid.org/0000-0002-7509-5695
Mark SpigtDepartment of Family Medicine, CAPHRI School for Public Health and Primary Care, Maastricht University, Maastricht, The Netherlands.
Afework Mulugeta BezabihSchool of Public Health, College of Health Sciences, Mekelle University, Mekelle, Ethiopia.
Geert-Jan DinantDepartment of Family Medicine, CAPHRI School for Public Health and Primary Care, Maastricht University, Maastricht, The Netherlands.
Roman Blanco VelascoDepartment of Surgery, School of Medicine, Alcala University, Madrid, Spain.
Maastricht University · NLMekelle University · ETUniversidad de Alcalá · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn marginalized setting, under-nutrition and illnesses due to infectious agents create a vicious circle. In our previous study, we reported that easy-to-do hand hygiene interventions were effective in preventing intestinal parasite infections (IPIs) and reduce the rate of anaemia among school-aged children. The aim of this study was to assess the pattern of associations between IPIs, anaemia and diarrhoea among the school-aged children and to explore if the observed impact of hand-washing and nail clipping interventions in our findings was similar across children with different baseline demographic and disease characteristics. The study was based on the analysis of data that was collected during the randomized controlled trial and hence have used the same study participants and study area.

resultsChildren with IPIs had a much higher chance of also being anaemic (AOR 2.09, 95% CI 1.15-3.80), having diarrhoea (AOR 2.83, 95% CI 1.57-5.09), and vice versa. Anaemia and diarrhoea were very strongly related (AOR 9.62, 95% CI 5.18-17.85). Overall, hand-washing with soap at key times and weekly nail clipping were efficacious in preventing intestinal parasite re-infection among children despite the differences in baseline demographic characteristics.

trial registrationNCT01619254 (June 09/2012).

Indexed as

Hand DisinfectionHand HygieneSchoolsAnemiaChildDiarrheaHumansIntestinal Diseases, ParasiticAnaemiaDiarrhoeaHand-washingIntestinal parasitic infectionsSchool-aged children

Identifiers

PMID31898526
PMCPMC6941294
OpenAlexW2998936405

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.