Evidence map›Paper›PMID 31898431›Full record

ArticleJournal of Korean medical science2020

Relationship between Cardiac Geometry and Serum Hepcidin in Chronic Kidney Disease: Analysis from the KNOW-CKD Study.

Hyang Ki Min, Yun Kyu Oh, Kyu Hun Choi, Kyu Beck Lee, Sue K Park, Curie Ahn, Sung Woo Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Korean medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Hepcidin as a Biomarker of Cardiorenal Syndrome.Journal of Korean medical science · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Hyang Ki MinDivision of Nephrology, Department of Internal Medicine, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-5883-234X
Yun Kyu OhDepartment of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0001-8632-5743
Kyu Hun ChoiDepartment of Internal Medicine, College of Medicine, Institute of Kidney Disease Research, Yonsei University, Seoul, Korea.ORCID https://orcid.org/0000-0003-0095-9011
Kyu Beck LeeDepartment of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3904-5404
Sue K ParkDepartment of Preventive Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5002-9707
Curie AhnDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2732-1619
Sung Woo LeeDivision of Nephrology, Department of Internal Medicine, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea. neplsw@gmail.com.ORCID https://orcid.org/0000-0002-4419-3938
Seoul National University · KREulji University · KRKangbuk Samsung Hospital · KRYonsei University · KR

Funding

Korea Centers for Disease Control & Prevention 2011E3300300Korea Centers for Disease Control & Prevention 2012E3301100Korea Centers for Disease Control & Prevention 2013E3301600Korea Centers for Disease Control & Prevention 2013E3301601Korea Centers for Disease Control & Prevention 2013E3301602Korea Centers for Disease Control & Prevention 2016E3300200Korea Centers for Disease Control & Prevention 2016E3300201Korea Centers for Disease Control & Prevention 2016E3300202
6 · The paper itself

Abstract

backgroundFew studies have examined the relationship between cardiac function and geometry and serum hepcidin levels in patients with chronic kidney disease (CKD). We aimed to identify the relationship between cardiac function and geometry and serum hepcidin levels.

methodsWe reviewed data of 1,897 patients in a large-scale multicenter prospective Korean study. Logistic regression analysis was used to identify the relationship between cardiac function and geometry and serum hepcidin levels.

resultsThe mean relative wall thickness (RWT) and left ventricular mass index (LVMI) were 0.38 and 42.0 g/m

conclusionAlthough the relationship was not cause-and-effect, increased RWT was independently associated with high serum hepcidin, particularly in women and patients with low TSAT. The relationship between cardiac geometry and serum hepcidin in CKD patients needs to be confirmed in future studies.

Indexed as

AdultAgedAnemiaEchocardiographyFemaleHeart VentriclesHepcidinsHumansLogistic ModelsMaleMiddle AgedOdds RatioProspective StudiesRenal Insufficiency, ChronicRisk FactorsSex FactorsHepcidinsTransferrinCardiac GeometryChronic Kidney DiseaseErythropoietin ResistanceHepcidinRelative Wall Thickness

Identifiers

PMID31898431
PMCPMC6942131
OpenAlexW2990447862

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.