Evidence map›Paper›PMID 31898209›Full record

ReviewCardiology and therapy2020

Catheter Ablation of Atrial Fibrillation: State of the Art and Future Perspectives.

Laura Rottner, Barbara Bellmann, Tina Lin, Bruno Reissmann, Tobias Tönnis, Ruben Schleberger, Moritz Nies, Christiane Jungen, Leon Dinshaw, Niklas Klatt and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Cardiology and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.

  1. Pulmonary vein isolation with adjunctive left atrial ganglionic plexus ablation for treatment of atrial fibrillation: a meta-analysis of randomized controlled trials.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2023
    Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Smart Catheters for Diagnosis, Monitoring, and Therapy.Advanced healthcare materials · 2026
    Review
  7. Intelligent Soft Opto-Magnetic Robot for Minimally Invasive Interventional Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Variability of baroreceptor reflex assessed by tilt table test in a patient undergoing pulmonary vein isolation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Observational
  13. Risk factors for the recurrence of atrial fibrillation after catheter ablation: a meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
    Review
  14. Article
  15. Article
  16. Electrographic flow mapping of atrial fibrillation.Current opinion in cardiology · 2025
    Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Laura RottnerUniversitäres Herzzentrum Hamburg-Eppendorf, Hamburg, Germany. laurarottner@aol.de.ORCID http://orcid.org/0000-0002-1389-8564
Barbara BellmannMEDIAN Klinik AGZ Düsseldorf, Düsseldorf, Germany.
Tina LinGenesisCare, East Melbourne, VIC, Australia.
Bruno ReissmannUniversitäres Herzzentrum Hamburg-Eppendorf, Hamburg, Germany.
Tobias TönnisUniversitäres Herzzentrum Hamburg-Eppendorf, Hamburg, Germany.
Ruben SchlebergerUniversitäres Herzzentrum Hamburg-Eppendorf, Hamburg, Germany.
Moritz NiesUniversitäres Herzzentrum Hamburg-Eppendorf, Hamburg, Germany.
Christiane JungenUniversitäres Herzzentrum Hamburg-Eppendorf, Hamburg, Germany.
Leon DinshawUniversitäres Herzzentrum Hamburg-Eppendorf, Hamburg, Germany.
Niklas KlattUniversitäres Herzzentrum Hamburg-Eppendorf, Hamburg, Germany.
Jannis DickowUniversitäres Herzzentrum Hamburg-Eppendorf, Hamburg, Germany.
Paula MünklerUniversitäres Herzzentrum Hamburg-Eppendorf, Hamburg, Germany.
Christian MeyerUniversitäres Herzzentrum Hamburg-Eppendorf, Hamburg, Germany.
Andreas MetznerUniversitäres Herzzentrum Hamburg-Eppendorf, Hamburg, Germany.
Andreas RilligUniversitäres Herzzentrum Hamburg-Eppendorf, Hamburg, Germany.
Universität Hamburg · DEAustralian and New Zealand Intensive Care Society · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewAtrial fibrillation (AF), the most common sustained arrhythmia, is associated with high rates of morbidity and mortality. Maintenance of stable sinus rhythm (SR) is the intended treatment target in symptomatic patients, and catheter ablation aimed at isolating the pulmonary veins provides the most effective treatment option, supported by encouraging clinical outcome data. A variety of energy sources and devices have been developed and evaluated. In this review, we summarize the current state of the art of catheter ablation of AF and describe future perspectives. RECENT

findingsCatheter ablation is a well-established treatment option for patients with symptomatic AF and is more successful at maintaining SR than antiarrhythmic drugs. Antral pulmonary vein isolation (PVI) as a stand-alone ablation strategy results in beneficial clinical outcomes and is therefore recommended as first-line strategy for both paroxysmal and persistent AF. While radiofrequency-based PVI in conjunction with a three-dimensional mapping system was for many years considered to be the "gold standard", the cryoballoon has emerged as the most commonly used alternative AF ablation tool, especially in patients with paroxysmal AF. Patients with persistent or long-standing persistent AF and with arrhythmia recurrence after previous PVI may benefit from additional ablation strategies, such as substrate modification of various forms or left atrial appendage isolation. New technologies and techniques, such as identification of the AF sources and magnetic resonance imaging-guided substrate modification, are on the way to further improve the success rates of catheter ablation for selected patients and might help to further reduce arrhythmia recurrence.

conclusionsPulmonary vein isolation is the treatment of choice for symptomatic patients with paroxysmal and persistent drug-refractory AF. The reconnection of previously isolated pulmonary veins remains the major cause of AF recurrence. Novel ablation tools, such as balloon technologies or alternative energy sources, might help to overcome this limitation. Patients with non-paroxysmal AF and with AF recurrence might benefit from alternative ablation strategies. However, further studies are warranted to further improve our knowledge of the underlying mechanisms of AF and to obtain long-term clinical outcomes on new ablation techniques.

Indexed as

Ablation techniquesAF sourcesAtrial fibrillationCatheter ablationCryoballoonDielectric mappingEPDKODEXRadiofrequencyRotor ablation

Identifiers

PMID31898209
PMCPMC7237603
OpenAlexW2997940034

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.