Evidence map›Paper›PMID 31897929›Full record

ArticleMaternal and child health journal2020

Neonatal Thyroxine, Maternal Thyroid Function, and Cognition in Mid-childhood in a US Cohort.

Samantha J Lain, Sheryl L Rifas-Shiman, Elizabeth N Pearce, Natasha Nassar, Emily Oken

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Maternal and child health journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samantha J LainChildren's Hospital At Westmead Clinical School, The University of Sydney, Sydney, Australia. Samantha.lain@sydney.edu.au.ORCID http://orcid.org/0000-0002-8988-7407
Sheryl L Rifas-ShimanDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, USA.
Elizabeth N PearceSection of Endocrinology, Diabetes and Nutrition, Boston University School of Medicine, Boston, MA, USA.
Natasha NassarChildren's Hospital At Westmead Clinical School, The University of Sydney, Sydney, Australia.
Emily OkenDivision of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, USA.

Funding

Prenatal environmental determinants of health in young adulthood: a lifecourse approachR01HD034568 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI Marie-France Hivert, Emily Oken · 1998 to 2026
$20.6M
Common and distinct early environmental influences on cardiometabolic and respiratory health: Mechanisms and methodsUH3OD023286 · OD · HARVARD PILGRIM HEALTH CARE, INC. · PI OKEN, EMILY · 2018 to 2022
$11.7M
Common and distinct early environmental influences on cardiometabolic and respiratory health: Mechanisms and methodsUG3OD023286 · OD · HARVARD PILGRIM HEALTH CARE, INC. · PI KLEINMAN, KENNETH P., OKEN, EMILY · 2016 to 2017
$4.1M
National Health and Medical Research Council Council Early Career Research Fellowship (1054751)National Institutes of Health (US) UG3 OD 023286NICHD NIH HHS R01 HD034568NIH HHS R01 HD 034568NIH HHS UG3 OD023286NIH HHS UH3 OD023286
6 · The paper itself

Abstract

objectiveExamine the associations of maternal thyroid hormones, maternal dietary information, and newborn T

methodsWe studied 921 children born 1999-2003 at gestational age ≥ 34 weeks, who were participants in Project Viva, a prospective pre-birth cohort study in Massachusetts. We examined maternal dietary information, maternal thyroid hormone levels, and neonatal levels of T

resultsWe included 514 women with measured first trimester thyroid hormone concentrations (mean 10.2 weeks); 15% of women had a thyroid stimulating hormone (TSH) level ≥ 2.5 mU/L, and 71% were college graduates. Newborn T CONCLUSIONS FOR PRACTICE: Maternal or neonatal thyroid hormone levels were not associated with cognitive outcomes in mid-childhood in this population with generally normal thyroid function. As we studied a highly educated cohort residing in an iodine-sufficient area, findings may not be generalizable.

Indexed as

Child DevelopmentChildCognitionCohort StudiesFemaleHumansInfantInfant, NewbornMaleMassachusettsProspective StudiesThyroid Function TestsThyroxineUnited StatesThyroxineChildhood cognitionMaternalNeonatalNewborn screeningThyroxine

Identifiers

PMID31897929
PMCPMC7083173

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.