Evidence map›Paper›PMID 31897888›Full record

ArticleInternational journal of hematology2020

High-dose dexamethasone therapy as the initial treatment for idiopathic thrombocytopenic purpura.

Ken Takase, Hirokazu Nagai, Moe Kadono, Takanori Yoshioka, Nobuyuki Yoshio, Yukio Hirabayashi, Takuo Ito, Morio Sawamura, Akihiro Yokoyama, Shinichiro Yoshida and 14 more

Open access · greenAbstract readCase ReportsLetter
PubMed Publisher
In one paragraph

Article in International journal of hematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 11 institutions in 1 country.

Ken TakaseDepartment of Hematology, National Hospital Organization Kyushu Medical Center, 1-8-1 Jigyohama, Chuo-ku, Fukuoka, 810-8563, Japan. takase.ken.fk@mail.hosp.go.jp.
Hirokazu NagaiDepartment of Hematology, National Hospital Organization Nagoya Medical Center, Nagoya, Japan.
Moe KadonoDepartment of Hematology, National Hospital Organization Hiroshimanishi Medical Center, Otake, Japan.
Takanori YoshiokaDepartment of Hematology, National Hospital Organization Okayama Medical Center, Okayama, Japan.
Nobuyuki YoshioDepartment of Hematology, National Hospital Organization Kanazawa Medical Center, Kanazawa, Japan.
Yukio HirabayashiDepartment of Hematology, National Hospital Organization Matsumoto Medical Center, Matsumoto Hospital, Matsumoto, Nagano, Japan.
Takuo ItoDepartment of Hematology, National Hospital Organization Kure Medical Center and Chugoku Cancer Center, Kure, Hiroshima, Japan.
Morio SawamuraDepartment of Clinical Research, National Hospital Organization Shibukawa Medical Center, Shibukawa, Gunma, Japan.
Akihiro YokoyamaDivision of Hematology, Department of Internal Medicine, Division of Transfusion Medicine, National Hospital Organization Tokyo Medical Center, Tokyo, Japan.
Shinichiro YoshidaDepartment of Hematology, National Hospital Organization Nagasaki Medical Center, Nagasaki, Japan.
Ikuyo TsutsumiDepartment of Hematology, National Hospital Organization Mito Medical Center, Ibaraki, Japan.
Maki OtsukaDepartment of Hematology, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan.
Youko SuehiroDepartment of Hematology, National Hospital Organization Kyushu Cancer Center, Fukuoka, Japan.
Michihiro HidakaDepartment of Hematology, National Hospital Organization Kumamoto Medical Center, Kumamoto, Japan.
Isao YoshidaDepartment of Hematology and Oncology, National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan.
Hisayuki YokoyamaDepartment of Hematology, National Hospital Organization Sendai Medical Center, Sendai, Japan.
Hitoshi InoueDepartment of Internal Medicine, National Hospital Organization Tsuruga Medical Center, Tsuruga, Japan.
Hiroatsu IidaDepartment of Hematology, National Hospital Organization Nagoya Medical Center, Nagoya, Japan.
Maki NakayamaDepartment of Hematology, National Hospital Organization Nishibeppu National Hospital, Beppu, Japan.
Terutoshi HishitaDepartment of Hematology, National Hospital Organization Himeji Medical Center, Himeji, Hyogo, Japan.
Hiromi IwasakiDepartment of Hematology, National Hospital Organization Kyushu Medical Center, 1-8-1 Jigyohama, Chuo-ku, Fukuoka, 810-8563, Japan.
Akiko KadaClinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan.
Akiko M SaitoClinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan.
Yoshiaki KurodaDepartment of Hematology, National Hospital Organization Hiroshimanishi Medical Center, Otake, Japan.
National Hospital Organization · JPNational Kyushu Medical Center · JPOhnishi Neurological Center · JPKagoshima Medical Center · JPKumamoto Medical Center · JPKure Medical Center · JPNagasaki Medical Center · JPNational Hospital Organization Kyushu Cancer Center · JPNational Hospital Organization Mito Medical Center · JPOkayama Medical Center · JPShikoku Cancer Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a controversy which short term high dose dexamethasone therapy (HDD) or standard dose prednisolone therapy as the initial treatment leads to long term efficacy in idiopathic thrombocytopenic purpura (ITP) patients. We conducted a multicenter, prospective trial to determine the efficacy and safety of short-term HDD in ITP patients aged 18-80 years with platelet counts of < 20 × 10

Indexed as

AdultDexamethasoneHumansMalePulse Therapy, DrugPurpura, Thrombocytopenic, IdiopathicTreatment OutcomeDexamethasoneHigh-dose dexamethasone therapyIdiopathic thrombocytopenic purpuraOpen-labelShort-termSingle-arm trial

Identifiers

PMID31897888
OpenAlexW2998683983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.