ArticleMikrochimica acta2020
Fluorometric and electrochemical dual-mode nanoprobe for tetracycline by using a nanocomposite prepared from carbon nitride quantum dots and silver nanoparticles.
Article in Mikrochimica acta, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 30 citations in OpenAlex.
- Bibliometrics Analysis of Research Progress of Electrochemical Detection of Tetracycline Antibiotics.Journal of analytical methods in chemistry · 2023Review
- Sandwich Fluorescence Detection of Foodborne PathogenFoods (Basel, Switzerland) · 2022Article
- Facile synthesis of carbon nitride quantum dots as a highly selective and sensitive fluorescent sensor for the tetracycline detection.RSC advances · 2021Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
A fluorometric and electrochemical dual-mode method is described for sensitive and specific detection of tetracycline (Tc). A novel nanoprobe was designed that is making use of a Tc-specific aptamer (apta), carbon nitride quantum dots (CNQDs) and silver nanoparticles (AgNPs). The aptamer was linked to the CNQDs which then were used as templates to synthesize the apta-CNQD@AgNP nanocomposites. The blue fluorescence of the nanocomposites (with excitation/emission maxima at 365/440 nm) is quenched. The addition of Tc leads to fluorescence recovery and a decrease in the electroconductivity of a gold electrode modified with apta-CNQD@AgNPs. The fluorometric method has a linear response in the 0.1 μM - 10 mM Tc concentration range and a 15 nM detection limit. The amperometric method (best performed at a working voltage of 0.21 V vs. Ag/AgCl) has a linear response in the 1 nM to 0.1 mM Tc concentration range and a 0.26 nM detection limit. Recoveries of Tc from spiked milk samples were comparable to data obtained by HPLC. Graphical abstractA fluorometric and electrochemical dual-mode nanoprobe (apta-CNQD@AgNPs) was prepared from aptamer (apta), carbon nitride quantum dots (CNQDs) and silver nanoparticles (AgNPs). The nanoprobe can be used for determination of tetracycline (Tc) based on fluorescence recovery of apta-CNQD@AgNPs and a decrease in the electroconductivity of a gold electrode modified with apta-CNQD@AgNPs.
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