SynthesisWorld journal of surgery2020
Meta-analysis of Enhanced Recovery After Surgery (ERAS) Protocols in Emergency Abdominal Surgery.
Synthesis in World journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05511194 (Safety and Efficacy of Enhanced Recovery After Surgery Therapeutic Protocol for Complicated Appendicitis in Children), which is not on this map. Cited by 59 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Safety and Efficacy of Enhanced Recovery After Surgery Therapeutic Protocol for Complicated Appendicitis in Children
Who cites it
59 citing papers in PubMed, 10 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Effect of enhanced recovery after surgery protocols on mortality and morbidity after trauma and non-trauma emergency laparotomies: a systematic review and meta-analysis.Updates in surgery · 2026Pooled it
- Efficacy and safety of therapeutic means for postoperative ileus: an umbrella review of meta-analyses.Langenbeck's archives of surgery · 2025Pooled it
- Enhanced recovery after surgery for adolescent idiopathic scoliosis: a revised systematic review and meta‑analysis.Spine deformity · 2025Pooled it
- Key interventions and outcomes in perioperative care pathways in emergency laparotomy: a systematic review.World journal of emergency surgery : WJES · 2025Pooled it
- Enhanced recovery after surgery protocols following emergency intra-abdominal surgery: a systematic review and meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Pooled it
- Protocolized care pathways in emergency general surgery: a systematic review and meta-analysis.The British journal of surgery · 2024Pooled it
- Evaluating the Impact of Enhanced Recovery After Surgery Protocols on Surgical Outcomes Following Bariatric Surgery-A Systematic Review and Meta-analysis of Randomised Clinical Trials.Obesity surgery · 2024Pooled it
- The effect of early oral postoperative feeding on the recovery of intestinal motility after gastrointestinal surgery: a systematic review and meta-analysis of randomized clinical trials.Frontiers in nutrition · 2024Pooled it
- Comparison of interventions and outcomes of enhanced recovery after surgery: a systematic review and meta-analysis of 2456 adolescent idiopathic scoliosis cases.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021Pooled it
- [Enhanced recovery after surgery-Does the ERAS concept keep its promises].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021Pooled it
- Short-term outcome following postoperative enhanced recovery implementation in patients with perforated peptic ulcer.European journal of medical research · 2025Trial
- Enhanced recovery programs following adhesive small bowel obstruction surgery are feasible and reduce the rate of postoperative ileus: a preliminary study.Langenbeck's archives of surgery · 2024Trial
- Adapted ERAS Pathway Versus Standard Care in Patients Undergoing Emergency Surgery for Perforation Peritonitis-a Randomized Controlled Trial.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Trial
- "Enhanced recovery after surgery - ERAS in elective craniotomies-a non-randomized controlled trial".BMC neurology · 2021Trial
- Long-term survival in generalized peritonitis: the impact of early critical periods in major emergency abdominal surgery.BMC surgery · 2026Article
- Predictors of Mortality and Modern Surgical Strategies in Intestinal Obstruction: A 200-Patient Study from a North Indian Tertiary Center.Annals of African medicine · 2026Article
- Impact of the Eras Protocols on Costs and Benefits in Two Italian Second-Level Healthcare Centers According to the National Waiting List Management Plan (PNGLA).Journal of clinical medicine · 2026Article
- Defining benchmarks for postoperative mobilization based on the recommendations of the Enhanced Recovery After Surgery (ERAS) program for liver surgery: a prospective study.Surgical endoscopy · 2025Observational
- Characterisation and evaluation of early mobilisation interventions after emergency laparotomy surgery: a scoping review.BJA open · 2025Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate enhanced recovery after surgery (ERAS) protocols in emergency abdominal surgery.
methodsThe electronic data sources were explored to capture all studies that evaluated the impact of ERAS protocols in patients who underwent emergency abdominal surgery. The quality of randomised and non-randomised studies was evaluated by the Cochrane tool and the Newcastle-Ottawa scale, respectively. Random or fixed effects modelling were utilised as indicated.
resultsSix comparative studies, enrolling 1334 patients, were eligible. ERAS protocols resulted in shorter post-operative time to first flatus (mean difference: -1.40, P < 0.00001), time to first defecation (mean difference: -1.21, P = 0.02), time to first oral liquid diet (mean difference: -2.30, P < 0.00001), time to first oral solid diet (mean difference: -2.40, P < 0.00001) and length of hospital stay (mean difference: -3.09, -2.80, P < 0.00001). ERAS protocols also resulted in lower risks of total complications (odds ratio: 0.50, P < 0.00001), major complications (odds ratio: 0.60, P = 0.0008), pulmonary complications (odds ratio: 0.38, P = 0.0003), paralytic ileus (odds ratio: 0.53, 0.88, P = 0.01) and surgical site infection (odds ratio: 0.39, P = 0.0001). Both ERAS and non-ERAS protocols resulted in similar risk of 30-day mortality (risk difference: -0.00, P = 0.94), need for re-admission (risk difference: -0.01, P = 0.50) and need for re-operation (odds ratio: 0.83, P = 0.50).
conclusionsAlthough ERAS protocols are commonly used in elective settings, they are associated with favourable outcomes in emergency settings as indicated by reduced post-operative complications, accelerated recovery of bowel function and shorter post-operative hospital stay without increasing need for re-admission or re-operation. There should be an effort to incorporate ERAS protocols into emergency abdominal surgery settings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.